Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Cryba1^{tm1a(EUCOMM)Hmgu}
Name:	crystallin, beta A1; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
MGI ID:	MGI:4951042
Synonyms:	beta3-, betaA3 KO

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Nuclear cataracts in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} mice	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Nuclear degradation process is impaired in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} mice	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Autophagic markers accumulate in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} mice	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Mitochondria accumulate in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} mice	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Fusion of autophagosomes with lysosomes in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} mouse lenses	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Calcium level is altered in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} lens epithelial cells	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Integrity of cytoskeletal network is affected in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} lenses	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Calpain-3 is activated in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} lenses	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N

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