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Phenotype Images associated with this Allele
Nomenclature
Symbol: Raf1tm1.1Bgn
Name: v-raf-leukemia viral oncogene 1; targeted mutation 1.1, Benjamin G Neel
MGI ID: MGI:5003364
Synonyms: Raf1L613V, Raf1tm1.1Ara
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Raf1tm1.1Bgn/Raf1+ mice show multiple Noonan syndrome phenotypes including short stature, facial dysmorphia and splenomegalyRaf1tm1.1Bgn/Raf1+involves: 129S6/SvEvTac * C57BL/6NCr
Raf1tm1.1Bgn/Raf1+ mice show cardiac hypertrophy with chamber dilatationRaf1tm1.1Bgn/Raf1+involves: 129S6/SvEvTac * C57BL/6NCr
Abnormal response of Raf1tm1.1Bgn/Raf1+ mice to pressure overloadRaf1tm1.1Bgn/Raf1+involves: 129S6/SvEvTac * C57BL/6NCr
Severe perivascular fibrosis in Raf1tm1.1Bgn/Raf1+ heart after transverse aortic constrictionRaf1tm1.1Bgn/Raf1+involves: 129S6/SvEvTac * C57BL/6NCr
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory