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Phenotype Images associated with this Allele
Nomenclature
Symbol: Mia3tm1Lex
Name: MIA SH3 domain ER export factor 3; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007248
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mia3tm1Lex/Mia3tm1Lex embryos are dwarfed, edemic, and fail to form a mineralized skeletonMia3tm1Lex/Mia3tm1Lexinvolves: 129S5/SvEvBrd * C57BL/6
Osteogenesis is compromised by the delay in chondrogenic progression and vascular recruitment in Mia3tm1Lex/Mia3tm1Lex boneMia3tm1Lex/Mia3tm1Lexinvolves: 129S5/SvEvBrd * C57BL/6
The endoplasmic reticulum is grossly distended, and collagen fibrils are reduced in Mia3tm1Lex/Mia3tm1Lex chondrocytesMia3tm1Lex/Mia3tm1Lexinvolves: 129S5/SvEvBrd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory