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Phenotype Images associated with this Allele
Nomenclature
Symbol: Tmem178tm1Lex
Name: transmembrane protein 178; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007374
Synonyms: Tmem178-
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Trabecular thinning and increase in osteoclast surface normalized to bone surface in Tmem178tm1Lex/Tmem178tm1Lex miceTmem178tm1Lex/Tmem178tm1Lexinvolves: 129S5/SvEvBrd * C57BL/6
Enhanced osteoclastogenesis in Tmem178tm1Lex/Tmem178tm1Lex miceTmem178tm1Lex/Tmem178tm1Lexinvolves: 129S5/SvEvBrd * C57BL/6
Tmem178tm1Lex/Tmem178tm1Lex mice suffer inflammatory osteolysisTmem178tm1Lex/Tmem178tm1Lexinvolves: 129S5/SvEvBrd * C57BL/6
Enhanced osteoclastogenesis in Tmem178tm1Lex/Tmem178tm1Lex miceTmem178tm1Lex/Tmem178tm1Lexinvolves: 129S5/SvEvBrd * C57BL/6
mgi:5007374/mgi:5007374 mice injected with LPS over the calvaria show increased osteoclast surfaceTmem178tm1Lex/Tmem178tm1Lexinvolves: 129S5/SvEvBrd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory