Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Akiyoshi Uemura
MGI ID:	MGI:5052360
Synonyms:	R26-Rhoj

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Retardation of retinal vascular growth in Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor⁺ Tg(Tek-cre)2352Rwng/0 mice	Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor⁺ Tg(Tek-cre)2352Rwng/0	involves: C57BL/6NCrlj * CBA/JNCrlj * FVB/N
	Membrane blebs form in endothelial cells of sprouting retinal vessels in Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(Tek-cre)#Rwng/0 and Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(CAG-cre/Esr1*)1Egwa/0 mice	Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(Tek-cre)#Rwng/0	involves: C57BL/6 * CBA
		Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(CAG-cre/Esr1*)1Egwa/0	involves: C57BL/6 * CBA * DBA/2
	Decreased extraretinal vascular outgrowth in ischemic Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(CAG-cre/Esr1*)1Egwa/0 retinas	Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(CAG-cre/Esr1*)1Egwa/0	involves: C57BL/6 * CBA * DBA/2
	Growth retardation and defective vascular development in Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(Tek-cre)#Rwng/0 mice	Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(Tek-cre)#Rwng/0	involves: C57BL/6 * CBA
	Unvascularized area is unchanged in retinas of Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(CAG-cre/Esr1*)1Egwa/0 mice following ROI despite an inncrease in the number of extraretinal vessels	Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem}/Gt(ROSA)26Sor^{tm1(CAG-Rhoj,-EGFP)Auem} Tg(CAG-cre/Esr1*)1Egwa/0	involves: C57BL/6 * CBA * DBA/2

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