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Phenotype Images associated with this Allele
Nomenclature
Symbol: Angpt1tm1.2Seq
Name: angiopoietin 1; targeted mutation 1.2, Susan E Quaggin
MGI ID: MGI:5140301
Synonyms: Angpt1del
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Loss of trabeculations in the heart of E9.5 and E10.5 Angpt1tm1.2Seq/Angpt1tm1.2Seq Kdrtm2.1Jrt/Kdr+ embryosAngpt1tm1.2Seq/Angpt1tm1.2Seq
Kdrtm2.1Jrt/Kdr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Angpt1tm1.2Seq/Angpt1tm1.2Seq Kdrtm2.1Jrt/Kdr+ embryos are grwoth restricted at E10.5 and have disorganized vasculatureAngpt1tm1.2Seq/Angpt1tm1.2Seq
Kdrtm2.1Jrt/Kdr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Impaired cardiac development in Angpt1tm1.2Seq/Angpt1tm1.2Seq Kdrtm2.1Jrt/Kdr+ embryosAngpt1tm1.2Seq/Angpt1tm1.2Seq
Kdrtm2.1Jrt/Kdr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory