Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Col12a1^tm1Debi
Name:	collagen, type XII, alpha 1; targeted mutation 1, David E Birk
MGI ID:	MGI:5141135

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Kyphosis in 5 month old Col12a1^tm1Debi/Col12a1^tm1Debi mice	Col12a1^tm1Debi/Col12a1^tm1Debi	involves: 129 * C57BL/6
	Reduction of cortical bone mass in Col12a1^tm1Debi/Col12a1^tm1Debi mice	Col12a1^tm1Debi/Col12a1^tm1Debi	involves: 129 * C57BL/6
	Decreased bone formation in Col12a1^tm1Debi/Col12a1^tm1Debi mice	Col12a1^tm1Debi/Col12a1^tm1Debi	involves: 129 * C57BL/6
	Disorganized bone matrix collagen arrangement in Col12a1^tm1Debi/Col12a1^tm1Debi mice	Col12a1^tm1Debi/Col12a1^tm1Debi	involves: 129 * C57BL/6
	Defective organization and polarization of osteoblasts in Col12a1^tm1Debi/Col12a1^tm1Debi bone	Col12a1^tm1Debi/Col12a1^tm1Debi	involves: 129 * C57BL/6
	Altered cell-cell interaction/communication in Col12a1^tm1Debi/Col12a1^tm1Debi bone in vivo	Col12a1^tm1Debi/Col12a1^tm1Debi	involves: 129 * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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