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Phenotype Images associated with this Allele
Nomenclature
Symbol: Col12a1tm1Debi
Name: collagen, type XII, alpha 1; targeted mutation 1, David E Birk
MGI ID: MGI:5141135
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Kyphosis in 5 month old Col12a1tm1Debi/Col12a1tm1Debi miceCol12a1tm1Debi/Col12a1tm1Debiinvolves: 129 * C57BL/6
Reduction of cortical bone mass in Col12a1tm1Debi/Col12a1tm1Debi miceCol12a1tm1Debi/Col12a1tm1Debiinvolves: 129 * C57BL/6
Decreased bone formation in Col12a1tm1Debi/Col12a1tm1Debi miceCol12a1tm1Debi/Col12a1tm1Debiinvolves: 129 * C57BL/6
Disorganized bone matrix collagen arrangement in Col12a1tm1Debi/Col12a1tm1Debi miceCol12a1tm1Debi/Col12a1tm1Debiinvolves: 129 * C57BL/6
Defective organization and polarization of osteoblasts in Col12a1tm1Debi/Col12a1tm1Debi boneCol12a1tm1Debi/Col12a1tm1Debiinvolves: 129 * C57BL/6
Altered cell-cell interaction/communication in Col12a1tm1Debi/Col12a1tm1Debi bone in vivoCol12a1tm1Debi/Col12a1tm1Debiinvolves: 129 * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory