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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dnah5b2b016Clo
Name: dynein, axonemal, heavy chain 5; Bench to Bassinet Program (B2B/CVDC), mutation 016 Cecilia Lo
MGI ID: MGI:5285078
Synonyms: Dakshi
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 016-030-LA presents with situs inversus totalis with dextrocardia, dextrogastria, and inverted lung and liver lobationDnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Videomicroscopy reveals slow ciliary motility within tracheal airway
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Dnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Mutant 016-007-LB shows situs inversus totalis with dextrocardia and inverted lung and liver lobationDnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Dextrocardia, right-sided stomach and pancreas (liver removed) and abnormal lung lobationDnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Mutant 016-0100-MLA exhibits situs inversus totalis with dextrocardia, dextrogastria, and inverted lung and liver lobationDnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Videomicroscopy reveals slow ciliary motility within tracheal airway
Click thumbnail to play movie.
Dnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Serial 2D EFIC image stack in the coronal plane of 016-002-LA reveals DORV {S,D,D}, common AV valve, and subaortic VSD
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Dnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Ultrasound imaging reveals VSDDnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Ultrasound imaging reveals AVSDDnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Coronal movie obtained by micro-CT scan reveals DORV {SDD}, common AV valve, and subaortic VSD
Click thumbnail to play movie.
Dnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
EFIC SummaryDnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Serial 2D EFIC image stack in the coronal plane of 016-010-NG reveals mirror image dextrocardia, mVSD, small ventricles, mLV hypertrophy, dilated atria, and dilated venous return
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Dnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Coronal movie obtained by microCT-scan reveals situs inversus totalis
Click thumbnail to play movie.
Dnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo
Mutant 016-037-LG exhibits slightly malaligned sternal vertebraDnah5b2b016Clo/Dnah5b2b016CloC57BL/6J-Dnah5b2b016Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory