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Phenotype Images associated with this Allele
Nomenclature
Symbol: Bicc1b2b222Clo
Name: BicC family RNA binding protein 1; Bench to Bassinet Program (B2B/CVDC), mutation 222 Cecilia Lo
MGI ID: MGI:5285079
Synonyms: Destro
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
2D serial EFIC image stacks in the coronal view reveals DORV, common atrium, AVSD and TAPVC
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Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
Situs inversus totalis with mirror image dextrocardia {I,L,I}Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
Situs inversus totalis.Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
Cystic kidneysBicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
2D serial EFIC image stacks in the coronal view reveals mirror image dextrocardia {I,L,I}
Click thumbnail to play movie.
Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
Pancreatic cyst and small spleenBicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
Videomicroscopy reveals tracheal airway cilia
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Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
Ultrasound imaging reveals AVSD
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Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
Ultrasound imaging reveals VSD and DORV
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Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
2D serial EFIC image stacks in the coronal view reveals d-TGA, common atria, AVSD, and IAA
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Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
Coronal movie obtained by micro-CT scan reveals DORV {SDD}, VSD, Pulmonary stenosis, and common AV valve
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Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
2D serial EFIC image stacks in the coronal view reveals d-TGA, intact ventricular septum, and double aortic arch
Click thumbnail to play movie.
Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
Dextrocardia and abnormal aortic arch (confirmed IAA by histopathology)Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
EFIC imaging reveals DORV, common atrium, AVSD and TAPVCBicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo
EFIC imaging reveals mirror image dextrocardia {I,L,I}Bicc1b2b222Clo/Bicc1b2b222CloC57BL/6J-Bicc1b2b222Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory