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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b464Clo
Name: Mutant line 464; Bench to Bassinet Program (B2B/CVDC), mutation 464 Cecilia Lo
MGI ID: MGI:5297424
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 464-003-NA presents with hypoplastic left ventricle, and hypoplastic aorta as confirmed by EFIC imaging.b2b464Clo/b2b464CloC57BL/6J-b2b464Clo
EFIC summaryb2b464Clo/b2b464CloC57BL/6J-b2b464Clo
2D serial EFIC image stack in the coronal view of 464-003-NA reveals Hypoplastic Left Heart Syndrome (HLHS) with hypoplastic aortic arch and aortic valve, hypoplastic left ventricle with small mitral valve, and ASD
Click thumbnail to play movie.		b2b464Clo/b2b464CloC57BL/6J-b2b464Clo
2D Serial EFIC image stack in the transverse view of 464-003-NA reveals hypoplastic aortic arch and aortic valve, hypoplastic left ventricle with small mitral valve
Click thumbnail to play movie.		b2b464Clo/b2b464CloC57BL/6J-b2b464Clo
2D Serial EFIC image stack in the sagittal view of 464-003-NA reveals hypoplastic aortic arch and aortic valve, hypoplastic left ventricle with small mitral valves
Click thumbnail to play movie.		b2b464Clo/b2b464CloC57BL/6J-b2b464Clo
Ultrasound imaging of mutant 464-003-NA reveals aortic reverse blood flowb2b464Clo/b2b464CloC57BL/6J-b2b464Clo
Ultrasound imaging of mutant 464-003-NA reveals aortic reverse blood flow in diastoleb2b464Clo/b2b464CloC57BL/6J-b2b464Clo
Ultrasound imaging in transverse view of mutant 464-003-NA reveals hypoplastic left ventricle (LV)b2b464Clo/b2b464CloC57BL/6J-b2b464Clo
Ultrasound imaging of mutant 464-003-NA reveals aortic reverse blood flow instead of forward blood flow
Click thumbnail to play movie.		b2b464Clo/b2b464CloC57BL/6J-b2b464Clo
Ultrasound imaging in transverse view of mutant 464-003-NA reveals hypoplastic left ventricle (LV)
Click thumbnail to play movie.		b2b464Clo/b2b464CloC57BL/6J-b2b464Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory