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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b370Clo
Name: Mutant line 370; Bench to Bassinet Program (B2B/CVDC), mutation 370 Cecilia Lo
MGI ID: MGI:5311366
Synonyms: Kitty
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Craniofacial abnormalities including proboscis, lack of mouth and lower jaw.b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
b2b370.1Clo/b2b370.1CloC57BL/6J-b2b370.1Clo
Coronal movie obtained from micro-CT scan reveals right aortic arch, cystic lung, and dilated bronchi
Click thumbnail to play movie.		b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
b2b370.1Clo/b2b370.1CloC57BL/6J-b2b370.1Clo
2D serial EFIC image stacks in the coronal view reveals right aortic arch and dilated bronchi
Click thumbnail to play movie.		b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
b2b370.1Clo/b2b370.1CloC57BL/6J-b2b370.1Clo
Cystic lungsb2b370Clo/b2b370CloC57BL/6J-b2b370Clo
b2b370.1Clo/b2b370.1CloC57BL/6J-b2b370.1Clo
Narrow, elongated great arteries with hypoplastic aortic arch.b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
b2b370.1Clo/b2b370.1CloC57BL/6J-b2b370.1Clo
Craniofacial abnormalities with proboscis and abnormal/absent maxilla-mandible with no mouth opening.b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
b2b370.1Clo/b2b370.1CloC57BL/6J-b2b370.1Clo
Right aortic arch with isolated left subclavian arteryb2b370Clo/b2b370CloC57BL/6J-b2b370Clo
b2b370.1Clo/b2b370.1CloC57BL/6J-b2b370.1Clo
b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
b2b370.1Clo/b2b370.1CloC57BL/6J-b2b370.1Clo
Coronal movie obtained by micro-CT scan reveals diphragmatic hernia, left lung hypoplasia and biventricular hypertrophy
Click thumbnail to play movie.		b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
Loxb2b370.2Clo/Loxb2b370.2CloC57BL/6J-Loxb2b370.2Clo
b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
Loxb2b370.2Clo/Loxb2b370.2CloC57BL/6J-Loxb2b370.2Clo
2D serial EFIC image stack in the coronal view reveals diaphragmatic hernia, left lung hypoplasia, and biventricular hypertrophy
Click thumbnail to play movie.		b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
Loxb2b370.2Clo/Loxb2b370.2CloC57BL/6J-Loxb2b370.2Clo
2D serial EFIC image stacks in the coronal view reveals supravalvular aortic stenosis, thickened great artery walls, biventricular hypertrophy and diaphragmatic hernia
Click thumbnail to play movie.		b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
Loxb2b370.2Clo/Loxb2b370.2CloC57BL/6J-Loxb2b370.2Clo
Narrowed ascending aorta and dilated pulmonary trunk with closing ductus arterosus.b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
Loxb2b370.2Clo/Loxb2b370.2CloC57BL/6J-Loxb2b370.2Clo
Diaphragmatic hernia with liver in the chest cavityb2b370Clo/b2b370CloC57BL/6J-b2b370Clo
Loxb2b370.2Clo/Loxb2b370.2CloC57BL/6J-Loxb2b370.2Clo
b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
Loxb2b370.2Clo/Loxb2b370.2CloC57BL/6J-Loxb2b370.2Clo
2D serial EFIC image stack in the coronal view reveals supravalvular aortic stenosis, ventricular hypertrophy, and pulmonary artery branch stenosis
Click thumbnail to play movie.		b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
Loxb2b370.2Clo/Loxb2b370.2CloC57BL/6J-Loxb2b370.2Clo
2D serial EFIC image stack in the sagittal view reveals supravalvular aortic stenosis, ventricular hypertrophy, and pulmonary artery branch stenosis
Click thumbnail to play movie.		b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
Loxb2b370.2Clo/Loxb2b370.2CloC57BL/6J-Loxb2b370.2Clo
2D serial EFIC image stack in the transverse view reveals supravalvular aortic stenosis, ventricular hypertrophy, and pulmonary artery branch stenosis
Click thumbnail to play movie.		b2b370Clo/b2b370CloC57BL/6J-b2b370Clo
Loxb2b370.2Clo/Loxb2b370.2CloC57BL/6J-Loxb2b370.2Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory