Phenotype Images associated with this Allele
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Nomenclature
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Symbol:
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b2b635Clo
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Name:
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Mutant line 635;
Bench to Bassinet Program (B2B/CVDC), mutation 635 Cecilia Lo
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MGI ID:
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MGI:5311367
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Synonyms:
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Ohia
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Images for
Allele
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Click images for details
 | Mutant 635-004-NA exhibits hypoplastic left ventricle and ascending arch hypoplasia, which was diagnosed as HLHS by EFIC imaging | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | Mutant 635-004-NA has a hypoplastic left ventricle | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | EFIC Summary | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | 2D Serial EFIC image stack in the coronal view of 635-004-NA reveals hypoplastic ascending aorta, hypoplastic aortic valve, and hypoplastic left ventricle with small mitral valve
Click thumbnail to play movie. | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | 3D EFIC reconstruction of 635-004-NA showing ascending aorta hypoplasia
Click thumbnail to play movie. | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | 2D Serial EFIC image stack in the transverse view of 635-004-NA reveals hypoplastic ascending aorta, hypoplastic aortic valve, hypoplastic left ventricle with small mitral valve
Click thumbnail to play movie. | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | 2D Serial EFIC image stack in the sagittal view of 635-004-NA reveals hypoplastic ascending aorta, hypoplastic aortic valve, and hypoplastic left ventricle with small mitral valve
Click thumbnail to play movie. | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | Mutant 635-004-NG has a kinked tail and micrognathia | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | Mutant 635-004-NG presents with a hypoplastic, interrupted aortic arch and hypoplastic left ventricle which lead to the diagnosis a HLHS spectrum phenotype | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | EFIC Summary | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | 2D Serial EFIC image stack in the coronal view of 635-004-NG reveals DORV, mesocardia, interrupted aortic arch, hypoplastic ascending aorta, and hypoplastic ventricle
Click thumbnail to play movie. | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | Ultrasound imaging of mutant 635-004-NG reveals hypoplastic left ventricle with reduced aortic blood flow indicating aortic hypoplasia
Click thumbnail to play movie. | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | Ultrasound imaging of mutant 635-004-NG reveals craniofacial defects (Bird face) | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | Ultrasound imaging of mutant 635-004-NG reveals hypoplastic left ventricle
Click thumbnail to play movie. | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | Ultrasound imaging of mutant 635-004-NG reveals hypoplastic left ventricle | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
 | Mutant 635-004-NG presents with micrognathia and enophthalmia of the left eye | b2b635Clo/b2b635Clo | C57BL/6J-b2b635Clo |
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