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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dync2h1b2b414Clo
Name: dynein cytoplasmic 2 heavy chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 414 Cecilia Lo
MGI ID: MGI:5311370
Synonyms: Dync2h1p.V234E, Lucifer
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
2D serial EFIC image stack in the coronal view reveals pulmonary atresia, AVSD, and MAPCAs
Click thumbnail to view movie.		Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
2D serial EFIC image stack in the transverse view reveals AVSD
Click thumbnail to view movie.		Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
PTA with single right lung lobeDync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Craniofacial defects including cyclopia and proboscisDync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
2D serial EFIC image stack in the coronal view reveals AVSD and overriding aorta
Click thumbnail to view movie.		Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
2D serial EFIC image stack in the transverse view reveals AVSD
Click thumbnail to view movie.		Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Pulmonary atresia with MAPCAs and duplicated IVC.Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
2D serial EFIC image stack in the coronal view reveals pulmonary atresia, AVSD, and MAPCA
Click thumbnail to view movie.		Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
2D serial EFIC image stack in the sagittal view reveals pulmonary atresia, AVSD, and MAPCAs
Click thumbnail to view movie.		Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Oligodactyly in the forelimbDync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Coronal movie obtained by micro-CT scan reveals mesocardia {SDD}, AVSD, Pulmonary atresia, Hypoplastic lung, and Hypotelorism
Click thumbnail to view movie.		Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Coronal movie obtained by micro-CT scan reveals mesocardia {SDD}, AVSD, Pulmonary atresia, and Hypoplastic lung
Click thumbnail to view movie.		Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Pulmonary atresia with MAPCADync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Pulmonary atresia with MAPCADync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Polydactyly and syndactyly in the right forelimbDync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Preaxial digit duplication in left forelimbDync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
2D serial EFIC image stack reveals MAPCA arising from the carotid artery
Click thumbnail to view movie.		Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
2D serial EFIC image stack in the coronal view reveals PTA, RAA, common atria, unbalanced AVSD, small RV lumen, ventricular hypertrophy, pulmonary artery from left carotid (MAPCA) and no coronary sinus
Click thumbnail to view movie.		Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Immunofluorescence of ureteric budDync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Immunofluorescence of ureteric budDync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Unilateral kidney agenesisDync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Dync2h1b2b414Clo/Dync2h1b2b414CloC57BL/6J-Dync2h1b2b414Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory