Phenotype Images associated with this Allele

Nomenclature

Symbol:	Dnah11^b2b598Clo
Name:	dynein, axonemal, heavy chain 11; Bench to Bassinet Program (B2B/CVDC) mutation 598, Cecilia Lo
MGI ID:	MGI:5311372
Synonyms:	Joplin

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 598-014-LV presents with situs inversus totalis including dextrocardia	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-014-LB presents with situs inversus totalis with dextrocardia, dextrogastria, inverted lung lobation, and inverted liver lobation	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-018-LA exhibits dextrocardia with biventricular hypertrophy, which is confirmed by EFIC imaging	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	EFIC Summary	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	2D Serial EFIC image stack in the coronal view of 598-018-LA reveals mirror image dextrocardia {I,L,I} and biventricular hypertrophy Click thumbnail to play movie.	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-018-LA presents with situs inversus totalis	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-018-LA exhibits hydronephrosis	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-018-LA is diagnosed with bilateral hydronephrosis of the kidney (left kidney shown)	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-014-LA presents with heterotaxy indicated by levocardia with left pulmonary isomerism, dextrogastria, and right sided liver	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-014-LA shows heterotaxy with levocardia and left pulmonary isomerism	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-014-LA shows cystic kidneys which is confirmed by histology	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-014-LA shows cystic dilations of the tubules in the kidney	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-014-LA exhibits hyperkinetic and immotile airway cilia Click thumbnail to play movie.	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-018-LE is diagnosed with situs inversus totalis	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-018-LE exhibits dextrogastria	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-018-LV presents wtih situs inversus totalis, including dextrocardia, dextrogastria, inverted lung lobation and inverted liver lobation	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	EFIC Summary	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	2D Serial EFIC image stack in the coronal plane of 598-034-MLA reveals mirror image dextrocardia Click thumbnail to play movie.	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-026-LB exhibits a malaligned sternum	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Videomicroscopy of tracheal airway cilia of mutant 598-026-LB reveals hyperkinetic, dyskinetic ciliary beat and areas of immotility Click thumbnail to play movie.	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Videomicroscopy of tracheal airway cilia of mutant 598-026-LB reveals hyperkinetic, dyskinetic ciliary beat and areas of immotility Click thumbnail to play movie.	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-021-LE presents with situs inversus totalis with dextrocardia	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	EFIC Summary	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	2D Serial EFIC image stack in the coronal view of 598-021-LE reveals mirror image dextrocardia, muscular VSD, and biventricular myocardial non-compaction Click thumbnail to play movie.	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo
	Mutant 598-021-LE has malaligned sternal vertebra	Dnah11^b2b598Clo/Dnah11^b2b598Clo	C57BL/6J-Dnah11^b2b598Clo

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