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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dnah5b2b1134Clo
Name: dynein, axonemal, heavy chain 5; Bench to Bassinet Program (B2B/CVDC), mutation 1134 Cecilia Lo
MGI ID: MGI:5311385
Synonyms: Dnahc5c.G482T, Razzle
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1134-007-MLC exhibits heterotaxy indicated by dextrocardia, lung lobation inversion, left liver isomerism and dextrogastriaDnah5b2b1134Clo/Dnah5b2b1134CloC57BL/6J-Dnah5b2b1134Clo
EFIC SummaryDnah5b2b1134Clo/Dnah5b2b1134CloC57BL/6J-Dnah5b2b1134Clo
Serial 2D EFIC image stack in the coronal plane of 1134-007-MLC shows mirror image dextrocardia
Click thumbnail to play movie.
Dnah5b2b1134Clo/Dnah5b2b1134CloC57BL/6J-Dnah5b2b1134Clo
Videomicroscopy of trachea in mutant 1134-007-MLC reveals immotile cilia
Click thumbnail to play movie.
Dnah5b2b1134Clo/Dnah5b2b1134CloC57BL/6J-Dnah5b2b1134Clo
Mutant 1134-005-MLB has situs inversus totalis indicated by dextrocardia and inverted outflowDnah5b2b1134Clo/Dnah5b2b1134CloC57BL/6J-Dnah5b2b1134Clo
Mutant 1134-005-MLB has situs inversus totalis with dextrogastria and hypoplastic spleenDnah5b2b1134Clo/Dnah5b2b1134CloC57BL/6J-Dnah5b2b1134Clo
Videomicroscopy of trachea in mutant 1134-005-MLB reveals immotile cilia
Click thumbnail to play movie.
Dnah5b2b1134Clo/Dnah5b2b1134CloC57BL/6J-Dnah5b2b1134Clo
Mutant 1134-006-LC has situs inversus totalisDnah5b2b1134Clo/Dnah5b2b1134CloC57BL/6J-Dnah5b2b1134Clo
EFIC SummaryDnah5b2b1134Clo/Dnah5b2b1134CloC57BL/6J-Dnah5b2b1134Clo
Serial 2D EFIC image stack in the coronal plane of 1134-006-LC shows mirror image dextrocardia and biventricular hypertrophy
Click thumbnail to play movie.
Dnah5b2b1134Clo/Dnah5b2b1134CloC57BL/6J-Dnah5b2b1134Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/09/2024
MGI 6.24
The Jackson Laboratory