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Phenotype Images associated with this Allele
Nomenclature
Symbol: Fuzb2b1273Clo
Name: fuzzy planar cell polarity protein; Bench to Bassinet Program (B2B/CVDC), mutation 1273 Cecilia Lo
MGI ID: MGI:5311392
Synonyms: octomouse
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Pulmonary atresia, dual IVC and single left lung lobe seen in mutant 1273-002-1 (E16.5)Fuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
EFIC SummaryFuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
2D serial EFIC image stack in the coronal view of mutant 1273-002-1 (E16.5) reveals pulmonary atresia, AVSD, right aortic arch, vascular sling, and hypoplastic lung
Click thumbnail to play movie.
Fuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
2D serial EFIC image stack in the transverse view of mutant 1273-002-1 (E16.5) reveals pulmonary atresia, AVSD, right aortic arch, vascular sling, hypoplastic lung, and TEF
Click thumbnail to play movie.
Fuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
Pulmonary atresia, single left lung lobe, right aortic arch and diaphragmatic hernia with liver protruding into chest cavity in mutant 1273-002-2 (E16.5)Fuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
EFIC SummaryFuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
2D serial EFIC image stack in the coronal view of mutant 1273-002-2 (E16.5) reveals pulmonary atresia, AVSD, right aortic arch, vascular sling, and hypoplastic lung
Click thumbnail to play movie.
Fuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
2D serial EFIC image stack in the transverse view of mutant 1273-002-2 (E16.5) reveals pulmonary atresia, AVSD, right aortic arch, vascular sling, hypoplastic lung, and TEF
Click thumbnail to play movie.
Fuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
Mutants 1273-002-1 and 2 (E16.5) show micrognathia and anophthalmia with severe hydropsFuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
Mutant 1273-002-2 (E16.5) show anophthalmia and craniofacial dysmorphismFuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
Mutant 1273-002-2 (E16.5) shows craniofacial dysmorphism with anophthalmiaFuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
Mutant 1273-002-2 (E16.5) shows forelimb central polydactyly with 9 digitsFuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
Mutant 1273-002-2 (E16.5) shows hindlimb polydactyly with preaxial digit duplicationFuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
Mutant 1273-002-2 (E16.5) shows hindlimb polydactyly with preaxial digit duplicationFuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
Mutant 1273-002-2 (E16.5) exhibit a shortened gutFuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo
Mutant 1273-002-2 (E16.5) show renal dysplasiaFuzb2b1273Clo/Fuzb2b1273CloC57BL/6J-Fuzb2b1273Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory