Phenotype Images associated with this Allele
Nomenclature
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Symbol:
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b2b251Clo
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Name:
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Mutant line 251;
Bench to Bassinet Program (B2B/CVDC), mutation 251 Cecilia Lo
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MGI ID:
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MGI:5313696
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Images for Allele
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Click images for details
| 2D serial EFIC images of mutant 251-005-1 (E18.5) in the coronal view reveals overriding aorta, perimembranous VSD (pmVSD), muscular VSD (mVSD), dysplastic aortic valve, and hypoplastic transvese aorta Click thumbnail to play movie. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| 2D serial EFIC images of mutant 251-007-1 (E15.5) in the coronal view reveals DORV {SDD}, non-commited VSD, muscular VSD (mVSD), dysplastic tricuspid and mitral valves, and non-compaction of ventricular myocardium Click thumbnail to play movie. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| 2D serial EFIC images of mutant 251-004-NA (newborn) in the transverse view reveals muscular VSD Click thumbnail to play movie. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| 2D serial EFIC images of mutant 251-005-1 (E18.5) in the transverse view reveals muscular and perimembranous VSDs (pmVSD). Click thumbnail to play movie. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| Malalignment of the great arteries suggest double outlet right ventricle (DORV) in mutant 251-007-1 (E15.5), which was subsequently confirmed by EFIC imaging. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| Transverse movie of mutant 251-004-NA obtained from micro-CT scan reveals muscular VSD (mVSD) Click thumbnail to play movie. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| Coronal movie of mutant 251-004-NA obtained from micro-CT scan reveals cystic lung Click thumbnail to play movie. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| 2D serial EFIC images of mutant 251-004-NA (newborn) in the coronal view reveals perimembranous VSD (pmVSD) and cystic lungs Click thumbnail to play movie. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| Color flow ultrasound imaging of fetus 251-005-1 (E18.5) showed aliasing in the aortic arch, indicating coarctation. Click thumbnail to play movie. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| Color flow ultrasound imaging of fetus 251-005-1 (E18.5) show aliasing at aortic arch, suggesting coarctation. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| Color flow Doppler imaging of fetus 251-005-1 (E18.5) in the transverse view showed VSD. Click thumbnail to play movie. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| Color flow ulrasound imaging in transverse view of fetus 251-005-1 (E18.5) show presence of VSD. | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
| | b2b251Clo/b2b251Clo | C57BL/6J-b2b251Clo |
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