Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Dctn5^b2b315Clo
Name:	dynactin 5; Bench to Bassinet Program (B2B/CVDC), mutation 315 Cecilia Lo
MGI ID:	MGI:5313698
Synonyms:	Nemo

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	2D serial EFIC image stack of 315-002-NB (newborn) in the coronal view reveals overriding aorta, VSD, thin right ventricle and hypoplastic lungs. Click thumbnail to play movie.	Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
	Tubule dilation or mild cystic disease	Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
	Tubule dilation or mild cystic disease	Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
		Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
		Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
	Mutant 315-006-NA exhibit micrognathia with severe hypoplasia of the lower jaw.	Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
	Mutant 315-006-NA show micrognathia with pointy snout and open eyelids.	Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
	2D serial EFIC image stack of mutant 315-006-NA in the coronal view reveals DORV and subaortic VSD Click thumbnail to play movie.	Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
	Mutant 315-004-2 exhibit cyclopia with anencephaly with no frontonasal process and no oral cavity.	Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
	Mutant 315-006-NA exhibit malalignment of the great arteries.	Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
	Mutant 315-007-NA exhibit severe micrognathia and microcephaly with now oral cavity and eyes shifted to the midline.	Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo
	Mutant 315-007-NA exhibit severe micrognathia and microcephaly with no mandible.	Dctn5^b2b315Clo/Dctn5^b2b315Clo	C57BL/6J-Dctn5^b2b315Clo

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