Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Hectd1^b2b327Clo
Name:	HECT domain E3 ubiquitin protein ligase 1; Bench to Bassinet Program (B2B/CVDC), mutation 327 Cecilia Lo
MGI ID:	MGI:5313700

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	2D serial EFIC image stack of mutant 327-006-1 in the coronal view reveals aortic atresia, hypoplastic aortic arch, VSD, abnormal pulmonary valve, and ventricular hypertrophy Click thumbnail to play movie.	Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
	Mutant 327-007-1 shows hypoplasia of the ascending aorta.	Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
	2D serial EFIC image stack of mutant 327-007-1 in the coronal view reveals the presence of a VSD, overriding aorta, aortic atresia, hypoplastic aortic arch, small RV, and ventricular hypertrophy Click thumbnail to play movie.	Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
		Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
	2D serial EFIC image stack of mutant 327-006-1 in the sagittal view reveals aortic atresia, hypoplastic aortic arch, patent ductus arteriosus, and ventricular hypertrophy Click thumbnail to play movie.	Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
	2D serial EFIC image stack of mutant 327-007-1 in sagittal view reveals aortic atresia, hypoplastic aortic arch, patent ductus arteriousus, and ventricular hypertrophy Click thumbnail to play movie.	Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
	2D serial EFIC image stack of mutant 327-007-1 in the transverse view reveals abnormal semi-lunar valves with cushion-like tissue and ventricular hypertrophy Click thumbnail to play movie.	Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
	2D serial EFIC image stack of mutant 327-007-3 in the coronal view reveals abnormal semilunar valves with cushion-like tissue and ventricular hypertrophy Click thumbnail to play movie.	Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
	2D serial EFIC image stack of mutant 327-004-NB in the coronal view reveals coronary fistula into right ventricle (RV). Click thumbnail to play movie.	Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
		Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
		Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo
		Hectd1^b2b327Clo/Hectd1^b2b327Clo	C57BL/6J-Hectd1^b2b327Clo

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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