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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b246Clo
Name: Mutant line 246; Bench to Bassinet Program (B2B/CVDC), mutation 246 Cecilia Lo
MGI ID: MGI:5313711
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
2D serial EFIC image stack of mutant 246-003-3 in the coronal view reveals DORV {SDD}, suboaortic VSD, hypoplastic PA, and common AV valve
Click thumbnail to play movie.		b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Parallel arrangement of aorta and pulmonary artery in mutant 246-007-2 indicates DORV confirmed by EFIC imagingb2b246Clo/b2b246CloC57BL/6J-b2b246Clo
EFIC imaging of mutant 246-003-3 in 3D volume rendering reveals DORV {SDD}, subaortic VSD, hypoplastic PA, and common AV valve
Click thumbnail to play movie.		b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
2D serial EFIC image stack of mutant 246-006-NA in the coronal view reveals DORV {SDD} and subpulmonary VSD (Taussig-Bing anomaly)
Click thumbnail to play movie.		b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Coronal movie of mutant 246-003-3 obtained by micro-CT scan reveals DORV {SDD}, subaortic VSD, hypoplastic PA, and common AV valve
Click thumbnail to play movie.		b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Coronal movie of mutant 246-006-NA obtained from micro-CT scan reveals holoprosencephaly, DORV {SDD}, and VSD
Click thumbnail to play movie.		b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Coronal movie mutant 246-004-NA obtained by micro-CT scan reveals DORV {SDD} and subaortic VSD
Click thumbnail to play movie.		b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
2D serial EFIC image stack of mutant 246-007-1 in the coronal view reveals DORV {SDD}, subaortic VSD, muscular VSD, and non-compaction of ventricular myocardium
Click thumbnail to play movie.		b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
2D serial EFIC image stack of mutant 246-006-NA in the coronal view reveals DORV {SDD} and subpulmonary VSD (Taissig-Bing anomaly)
Click thumbnail to play movie.		b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Parallel arrangement of aorta and pulmonary artery in mutant 246-007-1 indicates DORV confirmed by EFIC imagingb2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Color flow spectral Doppler imaging of mutant 246-003-3 in the sagittal view showed aortic flow from RV, with small adjacent vessel exhibiting now flow and VSD, indciating pulmonary atreisa with VSD.
Click thumbnail to play movie.		b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Color flow spectral Doppler imaging of mutant 246-003-3 in the transverse view showed inflow tract forward flow at endocardial cushion level, indicating AVSDb2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Color flow spectral Doppler imaging of mutant 246-003-3 in the transverse view showed inflow tract regurgitation at endocardial cushion level suggesting AVSD.b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Spectral doppler of mutant 246-003-3 reveals inflow tract regurgitationb2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Color flow imaging of mutant 246-003-3 in the sagittal view reveals VSD and Ao emerging from RV, and small vessel adjacent to Ao with now flow, indicating pulmonary atresia with VSD.b2b246Clo/b2b246CloC57BL/6J-b2b246Clo
EFIC summaryb2b246Clo/b2b246CloC57BL/6J-b2b246Clo
EFIC summaryb2b246Clo/b2b246CloC57BL/6J-b2b246Clo
EFIC summaryb2b246Clo/b2b246CloC57BL/6J-b2b246Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory