| Mutant 508-004-NL exhibits malalignment of the great arteries with blood congested atria and inferior vena cava (IVC). | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| 2D serial EFIC image stack of mutant 508-004-NL in the coronal view reveals double outlet right ventricle (DORV) and atrioventricular septal defect (AVSD). Click thumbnail to play movie. | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| 2D serial EFIC image stack of mutant 508-004-NH in the coronal view reveals double outlet right ventricle (DORV) and atrioventricular septal defect (AVSD). Click thumbnail to play movie. | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| 2D serial EFIC image stack of mutant 508-004-NK in the coronal view reveals double outlet right ventricle (DORV) and atrioventricular septal defect (AVSD). Click thumbnail to play movie. | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| Mutant 508-004-NL exhibits anopthalmia, microcephaly and micrognathia | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| Mutant 508-004-NL exhibits micrognathia with no lower jaw and no oral opening. | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| Mutant 508-004-NH kidney show absence of cilia (611-B1, red) in the collecting duct/ureteric bud (DBA, green). | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| Mutant 508-004-NH kidney show absence of cilia (611-B1, red) in the collecting duct/ureteric bud (DBA, green). | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| Mutant 508-004-NH kidney show absence of cilia (611-B1, red) in the collecting duct/ureteric bud (DBA, green). | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| Mutant 508-004-NH has abnormally shaped kidneys but no evidence of cystic disease. | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo | C57BL/6J-Smarca4b2b508.1Clo |
| Mutant 508-005-NA shows craniofacial defect with anencephaly. | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
b2b508.2Clo/b2b508.2Clo | C57BL/6J-b2b508.2Clo |
| EFIC Summary | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
b2b508.2Clo/b2b508.2Clo | C57BL/6J-b2b508.2Clo |
| Mutant 508-004-NE exhibit anopthalmia, microcephaly, absent mandibles, and low set pinnae. | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
b2b508.2Clo/b2b508.2Clo | C57BL/6J-b2b508.2Clo |
| Mutant 508-004-NE exhibit displaced pinnae and micrognathia with no mandible. | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
b2b508.2Clo/b2b508.2Clo | C57BL/6J-b2b508.2Clo |
| Mutant 508-004-NF exhibit anopthalmia, microcephaly, proboscis with no maxilla/mandible, and misplaced pinnae. | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
b2b508.2Clo/b2b508.2Clo | C57BL/6J-b2b508.2Clo |
| Mutant 508-004-NF exhibit anopthalmia, microcephaly with displaced pinnae, and micrognathia with no oral cavity. | b2b508Clo/b2b508Clo | C57BL/6J-b2b508Clo |
b2b508.2Clo/b2b508.2Clo | C57BL/6J-b2b508.2Clo |