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Phenotype Images associated with this Allele
Nomenclature
Symbol: Smad6b2b390Clo
Name: SMAD family member 6; Bench to Bassinet Program (B2B/CvDC), mutation 390 Cecilia Lo
MGI ID: MGI:5316777
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
2D serial EFIC image stack in the coronal view of mutant 390-006-1 (E14.5) reveals DORV {SDD}, subaortic VSD, and interrupted aortic arch (IAA type c)
Click thumbnail to play movie.		Smad6b2b390Clo/Smad6b2b390CloC57BL/6J-Smad6b2b390Clo
Transposition of the great arteries in mutant 390-005-4 (E16.5) confirmed by EFICSmad6b2b390Clo/Smad6b2b390CloC57BL/6J-Smad6b2b390Clo
Malpositioning of the outflow tract in mutant 390-006-2 (E14.5) confirmed by EFIC imagingSmad6b2b390Clo/Smad6b2b390CloC57BL/6J-Smad6b2b390Clo
Micro-CT scan in the coronal view of mutant 390-005-4 (E16.5) reveals TGA {SDD} and right ventricular hypertrophy
Click thumbnail to play movie.		Smad6b2b390Clo/Smad6b2b390CloC57BL/6J-Smad6b2b390Clo
EFIC summmarySmad6b2b390Clo/Smad6b2b390CloC57BL/6J-Smad6b2b390Clo
2D serial EFIC image stack in the coronal view of mutant 390-005-4 (E16.5) reveals TGA {SDD} and right ventricular hypertrophy
Click thumbnail to play movie.		Smad6b2b390Clo/Smad6b2b390CloC57BL/6J-Smad6b2b390Clo
2D serial EFIC image stack in the coronal view of mutant 390-006-2 (E14.5) reveals DORV {SDD} and subaortic VSD
Click thumbnail to play movie.		Smad6b2b390Clo/Smad6b2b390CloC57BL/6J-Smad6b2b390Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory