About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Nek8b2b1449Clo
Name: NIMA (never in mitosis gene a)-related expressed kinase 8; Bench to Bassinet Program (B2B/CVDC), mutation 1449 Cecilia Lo
MGI ID: MGI:5317588
Synonyms: Nek8Roc, Roc
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Heterotaxy indicated by levocardia, dual IVC and dextrogastriaNek8b2b1449Clo/Nek8b2b1449CloC57BL/6J-Nek8b2b1449Clo
Hypoplastic thymuses and duplicated inferior vena cavaNek8b2b1449Clo/Nek8b2b1449CloC57BL/6J-Nek8b2b1449Clo
Duplicated inferior vena cavaNek8b2b1449Clo/Nek8b2b1449CloC57BL/6J-Nek8b2b1449Clo
EFIC SummaryNek8b2b1449Clo/Nek8b2b1449CloC57BL/6J-Nek8b2b1449Clo
2D serial EFIC image stacks in the coronal view of mutant 1449-007-LA reveals muscular VSD {ADD} , bilateral IVC, hypoplastic right ventricle and left pulmonary isomerism
Click thumbnail to play movie.
Nek8b2b1449Clo/Nek8b2b1449CloC57BL/6J-Nek8b2b1449Clo
Mutant 1449-007-LA kidneys show hydronephrosis and hydroureterNek8b2b1449Clo/Nek8b2b1449CloC57BL/6J-Nek8b2b1449Clo
Normal tracheal airway cilia motility
Click thumbnail to play movie.
Nek8b2b1449Clo/Nek8b2b1449CloC57BL/6J-Nek8b2b1449Clo
Mutant 1440-002-LA kidneys show hydronephrosis, hydroureter, and glomerular cystsNek8b2b1449Clo/Nek8b2b1449CloC57BL/6J-Nek8b2b1449Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory