Phenotype Images associated with this Allele
Nomenclature
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Symbol:
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b2b977Clo
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Name:
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Mutant line 977;
Bench to Bassinet Program (B2B/CVDC), mutation 227 Cecilia Lo
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MGI ID:
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MGI:5318333
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Images for Allele
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Click images for details
| Transposition of the great arteries (TGA) confirmed by EFIC imaging in mutant 977-007-1 (E17.5) | b2b977Clo/b2b977Clo | C57BL/6J-b2b977Clo |
| EFIC summary | b2b977Clo/b2b977Clo | C57BL/6J-b2b977Clo |
| 2D serial EFIC image stack in the coronal view reveals TGA {SDD}, muscular VSD, and myocardial noncompaction in mutant 977-007-1 (E17.5) Click thumbnail to play movie. | b2b977Clo/b2b977Clo | C57BL/6J-b2b977Clo |
| Interrupted aortic arch (IAA) in mutant 977-007-3 (E17.5) | b2b977Clo/b2b977Clo | C57BL/6J-b2b977Clo |
| 2D serial EFIC image stack in the coronal plane of mutant 977-007-3 (ED17.5) reveals {SDD} DORV, VSD, total anomalous veinous return (to lSVC), and interrupted aortic artch type C Click thumbnail to play movie. | b2b977Clo/b2b977Clo | C57BL/6J-b2b977Clo |
| Mutant 977-002-ND exhibits malalignment of the great arteries, shown to be DORV by EFIC imaging | b2b977Clo/b2b977Clo | C57BL/6J-b2b977Clo |
| EFIC summary | b2b977Clo/b2b977Clo | C57BL/6J-b2b977Clo |
| 2D serial EFIC image stack in the coronal view of mutant 977-002-ND reveals DORV subaortic VSD, high take-off coronary arteries, and ventricular noncompaction Click thumbnail to play movie. | b2b977Clo/b2b977Clo | C57BL/6J-b2b977Clo |
| 2D microCT image stack in the coronal view of mutant 997-002-ND reveals DORV subaortic VSD, holoprosencephaly, and kidney agenesis Click thumbnail to play movie. | b2b977Clo/b2b977Clo | C57BL/6J-b2b977Clo |
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