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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b977Clo
Name: Mutant line 977; Bench to Bassinet Program (B2B/CVDC), mutation 227 Cecilia Lo
MGI ID: MGI:5318333
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Transposition of the great arteries (TGA) confirmed by EFIC imaging in mutant 977-007-1 (E17.5)b2b977Clo/b2b977CloC57BL/6J-b2b977Clo
EFIC summaryb2b977Clo/b2b977CloC57BL/6J-b2b977Clo
2D serial EFIC image stack in the coronal view reveals TGA {SDD}, muscular VSD, and myocardial noncompaction in mutant 977-007-1 (E17.5)
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b2b977Clo/b2b977CloC57BL/6J-b2b977Clo
Interrupted aortic arch (IAA) in mutant 977-007-3 (E17.5)b2b977Clo/b2b977CloC57BL/6J-b2b977Clo
2D serial EFIC image stack in the coronal plane of mutant 977-007-3 (ED17.5) reveals {SDD} DORV, VSD, total anomalous veinous return (to lSVC), and interrupted aortic artch type C
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b2b977Clo/b2b977CloC57BL/6J-b2b977Clo
Mutant 977-002-ND exhibits malalignment of the great arteries, shown to be DORV by EFIC imagingb2b977Clo/b2b977CloC57BL/6J-b2b977Clo
EFIC summaryb2b977Clo/b2b977CloC57BL/6J-b2b977Clo
2D serial EFIC image stack in the coronal view of mutant 977-002-ND reveals DORV subaortic VSD, high take-off coronary arteries, and ventricular noncompaction
Click thumbnail to play movie.
b2b977Clo/b2b977CloC57BL/6J-b2b977Clo
2D microCT image stack in the coronal view of mutant 997-002-ND reveals DORV subaortic VSD, holoprosencephaly, and kidney agenesis
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b2b977Clo/b2b977CloC57BL/6J-b2b977Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory