About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b977Clo
Name: Mutant line 977; Bench to Bassinet Program (B2B/CVDC), mutation 227 Cecilia Lo
MGI ID: MGI:5318333
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Transposition of the great arteries (TGA) confirmed by EFIC imaging in mutant 977-007-1 (E17.5)b2b977Clo/b2b977CloC57BL/6J-b2b977Clo
EFIC summaryb2b977Clo/b2b977CloC57BL/6J-b2b977Clo
2D serial EFIC image stack in the coronal view reveals TGA {SDD}, muscular VSD, and myocardial noncompaction in mutant 977-007-1 (E17.5)
Click thumbnail to play movie.
b2b977Clo/b2b977CloC57BL/6J-b2b977Clo
Interrupted aortic arch (IAA) in mutant 977-007-3 (E17.5)b2b977Clo/b2b977CloC57BL/6J-b2b977Clo
2D serial EFIC image stack in the coronal plane of mutant 977-007-3 (ED17.5) reveals {SDD} DORV, VSD, total anomalous veinous return (to lSVC), and interrupted aortic artch type C
Click thumbnail to play movie.
b2b977Clo/b2b977CloC57BL/6J-b2b977Clo
Mutant 977-002-ND exhibits malalignment of the great arteries, shown to be DORV by EFIC imagingb2b977Clo/b2b977CloC57BL/6J-b2b977Clo
EFIC summaryb2b977Clo/b2b977CloC57BL/6J-b2b977Clo
2D serial EFIC image stack in the coronal view of mutant 977-002-ND reveals DORV subaortic VSD, high take-off coronary arteries, and ventricular noncompaction
Click thumbnail to play movie.
b2b977Clo/b2b977CloC57BL/6J-b2b977Clo
2D microCT image stack in the coronal view of mutant 997-002-ND reveals DORV subaortic VSD, holoprosencephaly, and kidney agenesis
Click thumbnail to play movie.
b2b977Clo/b2b977CloC57BL/6J-b2b977Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory