Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Nr1h3^tm1.1Djm
Name:	nuclear receptor subfamily 1, group H, member 3; targeted mutation 1.1, David J Mangelsdorf
MGI ID:	MGI:5426973
Synonyms:	Lxra^fl

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Atherosclerosis lesion area is increased in Ldlr^tm1Her/Ldlr^tm1Her Nr1h3^tm1.1Djm/Nr1h3^tm1.1Djm Speer6-ps1^{Tg(Alb-cre)21Mgn}/0 mice and TO901317 treatment reduces these lesions	Ldlr^tm1Her/Ldlr^tm1Her Nr1h3^tm1.1Djm/Nr1h3^tm1.1Djm Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺	involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * DBA
	Increase in macrophage content in Ldlr^tm1Her/Ldlr^tm1Her Nr1h3^tm1.1Djm/Nr1h3^tm1.1Djm Speer6-ps1^{Tg(Alb-cre)21Mgn}/0 aortic root	Ldlr^tm1Her/Ldlr^tm1Her Nr1h3^tm1.1Djm/Nr1h3^tm1.1Djm Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺	involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * DBA

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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