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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dnah5b2b1565Clo
Name: dynein, axonemal, heavy chain 5; Bench to Bassinet Program (B2B/CVDC), mutation 1565 Cecilia Lo
MGI ID: MGI:5430344
Synonyms: Dnahc5c.T13210A, Sleepy
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1565-004-NA displays dextrocardia with right aortic arch and normal relative great artery positioningDnah5b2b1565Clo/Dnah5b2b1565CloC57BL/6J-Dnah5b2b1565Clo
EFIC SummaryDnah5b2b1565Clo/Dnah5b2b1565CloC57BL/6J-Dnah5b2b1565Clo
2D serial EFIC image stack in the coronal plane of 1565-004-NA reveals mirror image dextrocardia with mirror symmetric positioning of great arteries, aortic arch, and lung lobation
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Dnah5b2b1565Clo/Dnah5b2b1565CloC57BL/6J-Dnah5b2b1565Clo
2D micro-MRI image stack in the coronal imaging plane of 1565-004-NA reveals dextracardia {ILI} associated with situs inversus totalis
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Dnah5b2b1565Clo/Dnah5b2b1565CloC57BL/6J-Dnah5b2b1565Clo
Mutant 1565-004-NA displays situs inversus totalis indicated by dextrocardia and mirror symmetric positioning of all visceral organ situsDnah5b2b1565Clo/Dnah5b2b1565CloC57BL/6J-Dnah5b2b1565Clo
Mutant 1565-004-LA displays situs inverses totalis indicated by mirror symmetric placement of the heart and all visceral organs.Dnah5b2b1565Clo/Dnah5b2b1565CloC57BL/6J-Dnah5b2b1565Clo
Immotile cilia in the trachel airway epithelia of mutant 1565-004-LA
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Dnah5b2b1565Clo/Dnah5b2b1565CloC57BL/6J-Dnah5b2b1565Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory