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Phenotype Images associated with this Allele
Nomenclature
Symbol: Gt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Frank J Slack
MGI ID: MGI:5431136
Synonyms: Gt(ROSA)26Sortm1(tetO-Mir155)Fjsl, mir-155LSLtTA
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Gt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/Gt(ROSA)26Sor+ Tg(Nes-cre)1Wmz/0 mice develop disseminated lymphomaGt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/Gt(ROSA)26Sor+
Tg(Nes-cre)1Wmz/0		involves: 129 * C57BL/6 * FVB/N * SJL/J
Doxycycline-induced withdrawal of Mir155 leads to rapid tumor regression in Gt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/Gt(ROSA)26Sor+ Tg(Nes-cre)1Wmz/0 miceGt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/Gt(ROSA)26Sor+
Tg(Nes-cre)1Wmz/0		involves: 129 * C57BL/6 * FVB/N * SJL/J
Expanding white pulp in Gt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/Gt(ROSA)26Sor+ Tg(Nes-cre)1Wmz/0 miceGt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/Gt(ROSA)26Sor+
Tg(Nes-cre)1Wmz/0		involves: 129 * C57BL/6 * FVB/N * SJL/J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory