About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Gm572b2b1167Clo
Name: predicted gene 572; Bench to Bassinet Program (B2B/CVDC), mutation 1167 Cecilia Lo
MGI ID: MGI:5431499
Synonyms: Glow
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1167-020-LB shows heterotaxy with right lung isomerismGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Mutant 1167-020-LB exhibits TGAGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
EFIC SummaryGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Serial 2D EFIC image stack in the coronal plane of mutant 1167-020-LB reveals TGA (S,D,D), AVSD, mVSD, ventricular noncompaction, and right lung isomerism
Click thumbnail to play movie.		Gm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Mutant 1167-003-4 (E15.5) exhibits dextrocardia with right aortic arch, normal relative great artery positioning and mid-live liverGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
EFIC SummaryGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Serial 2D EFIC image stack in the coronal plane of mutant fetus 1167-003-4 (E15.5) reveals DORV {A,L,L}, AVSD, and right pulmonary isomerism
Click thumbnail to play movie.		Gm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Mutant 1167-003-1 (E15.5) is diagnosed with DORV by EFICGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
EFIC SummaryGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Serial 2D EFIC image stack of 1167-003-1 (E15.5) in the coronal imaging plane reveals DORV, AVSD, muscular VSD, and ventricular non-compaction
Click thumbnail to play movie.		Gm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Ultrasound color flow imaging in the transverse plane of fetus 1167-003-1 (E15.5) showed an endocardial cushion defect indicative of an atrioventricular septal defect (AVSD)Gm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Ultrasound color flow imaging in the frontal view of fetus 1167-003-1 (E15.5) showed the aorta and pulmonary artery side by side emerging from RV, with a subaortic VSD suggesting a DORVGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Mutant 1167-004-LA exhibits situs inversus totalisGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Mutant 1167-003-NA exhibits levocardia with right aortic arch and normal lung lobationGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
EFIC SummaryGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Serial 2D EFIC image stack in the coronal plane of 1167-003-NA reveals right aortic arch, bilateral PDA, thickened ventricular wall
Click thumbnail to play movie.		Gm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Mutant 1167-004-LA shows inverted kidney positioningGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Immunofluorescence of cross-sections of kidney proximal tubules show very long cilia (red)Gm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Mutant 1167-018-LA exhibits heterotaxy with dextrocardia with normal gut situs and hypoplastic thymusGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Mutant 1167-018-LA presents with TGA and hypoplastic morphological RVGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
EFIC SummaryGm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Serial 2D EFIC image stack in the coronal plane of 1167-018-LA reveals dextrocardia, D-TGA (A,D,D), hypoplastic mRV, unbalanced AVSD, mVSD, dual IVC, malalignment of OFT (Ao anterior to PA), and right atrial isomerism
Click thumbnail to play movie.		Gm572b2b1167Clo/Gm572b2b1167CloC57BL/6J-Gm572b2b1167Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory