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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b1436Clo
Name: Mutant line 1436; Bench to Bassinet Program (B2B/CVDC), mutation 1436 Cecilia Lo
MGI ID: MGI:5431500
Synonyms: Baby Beluga
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1436-002-LA displays situs inversus totalisb2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo
Mutant 1436-002-LA displays dextrocardia, right aortic arch and dual IVCb2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo
EFIC Summaryb2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo
Serial 2D EFIC image stack in the coronal plane of 1436-002-LA reveals AVSD {ALI}, bilateral IVC, and has a single right lobe and 2 left lung lobes
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b2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo
2D MRI scan in the coronal plane of 1436-002-LA reveals Dextrocardia, AVSD, bilateral IVC, dextrogastria, left-sided lung lobation pattern, Heterotaxia, cleft palate.
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b2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo
Mutant 1436-006-1 (E15.5) displays levocardia with TGA confirmed by microCT scanb2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo
2D micro-CT scan in the coronal plane of 1436-006-1 (E14.5) reveals {SDD} d-TGA, AVSD, and small RV
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b2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo
Ultrasound 2D imaging movie in the frontal view of fetus 1436-006-1 (E15.5) showed the aorta and pulmonary artery side by side, the aorta originating from RV and the pulmonary artery emerging from LV, which together suggests TGA
Click thumbnail to play movie.
b2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo
Ultrasound 2D imaging in the frontal view of fetus 1436-006-1 (E15.5) showed the aorta and pulmonary artery side by side, the aorta originating from RV and the pulmonary artery emerging from LV, which together suggests TGAb2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo
Ultrasound color flow imaging movie in the frontal view of fetus 1436-006-1 (E15.5) showed the aorta and pulmonary artery side by side, with the aorta originating from RV and the pulmonary artery from LV, which together suggests TGA associated with a small VSD
Click thumbnail to play movie.
b2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo
Ultrasound color flow imaging in the frontal view of fetus 1436-006-1 (E15.5) showed the aorta and pulmonary artery side by side, with the aorta originating from RV and the pulmonary artery coming from LV, which together suggests TGA associated with a small VSDb2b1436Clo/b2b1436CloC57BL/6J-b2b1436Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory