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Phenotype Images associated with this Allele
Nomenclature
Symbol: Vps18tm1.1Wtao
Name: VPS18 CORVET/HOPS core subunit; targeted mutation 1.1, Wufan Tao
MGI ID: MGI:5431976
Synonyms: Vsp18F
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Small size of Vps18tm1.1Wtao/Vps18tm1.1Wtao Tg(Nes-cre)1Kln/0 mice at P10Vps18tm1.1Wtao/Vps18tm1.1Wtao
Tg(Nes-cre)1Kln/0		involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL
Smaller cerebrums and cerebellums in Vps18tm1.1Wtao/Vps18tm1.1Wtao Tg(Nes-cre)1Kln/0 miceVps18tm1.1Wtao/Vps18tm1.1Wtao
Tg(Nes-cre)1Kln/0		involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL
Neurodegeneration in Vps18tm1.1Wtao/Vps18tm1.1Wtao Tg(Nes-cre)1Kln/0 and Vps18tm1.1Wtao/Vps18tm1.1Wtao Tg(Pcp2-cre)2Mpin/0 brainsVps18tm1.1Wtao/Vps18tm1.1Wtao
Tg(Nes-cre)1Kln/0		involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL
Vps18tm1.1Wtao/Vps18tm1.1Wtao
Tg(Pcp2-cre)2Mpin/0		B.129-Vps18tm1.1Wtao Tg(Pcp2-cre)2Mpin
Accumulation of autophagosomes, late endosomes and amorphous densely stained vesicles in Vps18tm1.1Wtao/Vps18tm1.1Wtao Tg(Nes-cre)1Kln/0 brainsVps18tm1.1Wtao/Vps18tm1.1Wtao
Tg(Nes-cre)1Kln/0		involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory