Phenotype Images associated with this Allele

Nomenclature

Symbol:	Ap1b1^b2b1660Clo
Name:	adaptor protein complex AP-1, beta 1 subunit; Bench to Bassinet Program (B2B/CVDC), mutation 1660 Cecilia Lo
MGI ID:	MGI:5433323
Synonyms:	Pistachio

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 11660-002-LA exhibits dextrocardia with situs inversus and possible bile duct obstruction	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-002-LA exhibits dextrogastria	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-002-LA with mirror image dextrocardia with inverted lung lobation	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 160-002-LA with hypoplastic spleen	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-002-LA with malaligned sternovertebrae	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-002-LA showing abormal kidney positioning at the same anterior-posterior level	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Tracheal airway epithelia from mutant 1660-002-LA show dyskinetic ciliary motion Click thumbnail to play movie.	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-003-LA exhibits levocardia and normal liver situs, but with left pulmonary isomerism	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-003-LA exhibits asplenia	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-003-LA exhibits abnormal positioning of both kidneys at same anterior-posterior axial level	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	EFIC Summary	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Serial 2D EFIC image stack in the coronal plane of 1660-003-LA reveals bilateral IVC, bilateral single lung lobe Click thumbnail to play movie.	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-003-LA respiratory epithelia show areas of dyskinetic cilia motility and immotile cilia Click thumbnail to play movie.	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Tracheal airway epithelia from mutant 1660-003-LA show dyskinetic ciliary motility Click thumbnail to play movie.	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-003-LB exhibits asplenia	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-003-LB exhibits malaligned sternovertebrae	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-004-LA exhibits situs inversus totalis	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-004-LA exhibits hypoplastic spleen	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-004-LA exhibits hypoplastic spleen	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo
	Mutant 1660-004-LA exhibits abnormal kidney situs bilaterally at the anterior-posterior level	Ap1b1^b2b1660Clo/Ap1b1^b2b1660Clo	C57BL/6J-Ap1b1^b2b1660Clo

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