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Phenotype Images associated with this Allele
Nomenclature
Symbol: Tmem67b2b1163.1Clo
Name: transmembrane protein 67; Bench to Bassinet Program (B2B/CVDC), subline 1163.1 Cecilia Lo
MGI ID: MGI:5433409
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1163-006-NA displays malpositioned heart with interrupted aorta and DORV (confirmed by EFIC imaging)b2b1163Clo/b2b1163CloC57BL/6J-b2b1163Clo
Tmem67b2b1163.1Clo/Tmem67b2b1163.1CloC57BL/6J-Tmem67b2b1163.1Clo
Mutant 1163-006-NA displays heterotaxy indicated by mesocardia, dextrogastria and malrotated gutb2b1163Clo/b2b1163CloC57BL/6J-b2b1163Clo
Tmem67b2b1163.1Clo/Tmem67b2b1163.1CloC57BL/6J-Tmem67b2b1163.1Clo
EFIC Summaryb2b1163Clo/b2b1163CloC57BL/6J-b2b1163Clo
Tmem67b2b1163.1Clo/Tmem67b2b1163.1CloC57BL/6J-Tmem67b2b1163.1Clo
Serial 2D EFIC image stack in the coronal plane of 1163-006-NA reveals DORV, AVSD (non-commited) {SDD}, interrupted aortic arch (type-B), isolated right subclavian artery from descending aorta
Click thumbnail to play movie.		b2b1163Clo/b2b1163CloC57BL/6J-b2b1163Clo
Tmem67b2b1163.1Clo/Tmem67b2b1163.1CloC57BL/6J-Tmem67b2b1163.1Clo
Mutant 1163-006-NA displays cystic kidneys (indicated by light spots shining through, confirmed by histology)b2b1163Clo/b2b1163CloC57BL/6J-b2b1163Clo
Tmem67b2b1163.1Clo/Tmem67b2b1163.1CloC57BL/6J-Tmem67b2b1163.1Clo
Mutant 1163-006-NA shows cystic kidneys with cysts in the tubulesb2b1163Clo/b2b1163CloC57BL/6J-b2b1163Clo
Tmem67b2b1163.1Clo/Tmem67b2b1163.1CloC57BL/6J-Tmem67b2b1163.1Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory