Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Dnah11^b2b1289Clo
Name:	dynein, axonemal, heavy chain 11; Bench to Bassinet Program (B2B/CVDC) mutation 1289, Cecilia Lo
MGI ID:	MGI:5437083
Synonyms:	Dnahc11^c.A5632G, Ghost

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 1289-003-NA shows levocardia, right aortic arch and ambiguous lung lobation	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	EFIC Summary	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Serial 2D EFIC image stack in the coronal plane of 1289-003-NA reveals right aortic arch, mVSDs, biventricular hypertrophy and isolated left subclavian artery forming vascular sling Click thumbnail to play movie.	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Mutant 1289-003-LA exhibits heterotaxy with levocardia, dextrogastria, midline liver, and polysplenia	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Mutant 1289-003-LA reveals levocardia with left lung isomerism	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Mutant 1289-003-LA exhibits polysplenia with right sided stomach	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Mutant 1289-003-LA reveals malaligned sternal vertebrae	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Videomicroscopy of 1289-003-LA mutant airway reveals motile airway cilia Click thumbnail to play movie.	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Immunofluorescence of ureteric bud	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Mutant 1289-019-LC presents with microphthalmia of the left eye	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Mutant 1289-019-LC presents with anophthalmia of the right eye	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Mutant 1289-019-LC exhibits a hypoplastic spleen	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Mutant 1289-019-LC presents with a duplex right kidney that also exhibits hydronephrosis and cysts which is confirmed by histology	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo
	Right kidney of mutant 1289-019-LC is duplex with likely hydronephrosis and hydroureter. It is also cystic dysplastic	Dnah11^b2b1289Clo/Dnah11^b2b1289Clo	C57BL/6J-Dnah11^b2b1289Clo

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