| Mutant 227-002-NC exhibits dextrocardia with duplicated inferior vena cava (IVC) and parallel outflow tracts which is diagnosed as DORV by EFIC imaging | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Mutant 227-002-NC exhibits dextrocardia with inverted liver lobation | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| EFIC Summary | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Serial 2D EFIC image stack of 227-007-NC in the coronal plane reveals dextrocardia, DORV, AVSD (subaortic) {A,L,L} Click thumbnail to play movie. | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Mutant 227-127-LB displays dextrocardia, dextrogastria and left sided liver indicative of heterotaxy | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Mutant 227-127-LB displays dextrocardia, dextrogastria and a small spleen | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| EFIC Summary | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Serial 2D EFIC image stack in the coronal plane of 227-127-LB reveals mirror image dextrocardia and mVSD Click thumbnail to play movie. | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Mutant 227-127-LB displays dextrogastria and midline liver | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Videomicroscopy of mutant 227-127-LB airway cilia reveals patches of immotile and dyskinetic cilia Click thumbnail to play movie. | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Mutant 227-002-NB displays mesocardia and cystic lungs | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| EFIC Summary | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Serial 2D EFIC image stack in the coronal plane of 227-002-NB reveals mesocardia, mVSD, dilated atria/ventricle, lung cysts, and dilated venous return Click thumbnail to play movie. | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Mutant 227-118-LA exhibits dextrocardia with RAA, hypoplastic morphological RV, and dual IVC which is confirmed by EFIC imaging | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| EFIC Summary | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Serial 2D EFIC image stack in the coronal plane of 227-118-LA reveals dextrocardia, hypoplastic mRV, mVSD, right atrial isomerism, and dual IVC Click thumbnail to play movie. | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Mutant 227-118-LA has malaligned sternal vertebra | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
Odad2b2b227.1Clo/Odad2b2b227.1Clo | C57BL/6J-Odad2b2b227.1Clo |
| Serial 2D EFIC image stack of 227-002-ND in coronal plane reveals ventricular septal hypertrophy Click thumbnail to play movie. | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
b2b227.2Clo/b2b227.2Clo | C57BL/6J-b2b227.2Clo |
| 2D micro-MRI image stack of 227-085-LA in coronal plane reveals ventricular hypertrophy Click thumbnail to play movie. | b2b227Clo/b2b227Clo | C57BL/6J-b2b227Clo |
b2b227.2Clo/b2b227.2Clo | C57BL/6J-b2b227.2Clo |