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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b1298Clo
Name: Mutant line 1298; Bench to Bassinet Program (B2B/CVDC), mutation 1298 Cecilia Lo
MGI ID: MGI:5437729
Synonyms: Camel
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
1298-004-NA exhibits interrupted aortic archb2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
EFIC Summaryb2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Serial 2D EFIC image stack in the coronal plane of mutant 1298-004-NA reveals DORV {S,D,D}, subaortic VSD , AVSD, muscular VSD, interrupted aortic arch (type B)
Click thumbnail to play movie.		b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
1298-005-LA exhibits malalignment of the great artery indicating possible double outlet right ventricle (DORV) and also interrupted aortic arch (type B).b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
EFIC Summaryb2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Serial 2D EFIC image stack in the coronal plane of 1298-005-LA exhibits DORV subaortic VSD, inuterrupted aortic arch (type B)
Click thumbnail to play movie.		b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Mutant 1298-005-LC exhibits malalignment of the great arteries, narrowing of the ascending aorta, and an interrupted aortic arch (type B).b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
EFIC Summaryb2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Serial 2D EFIC image stack in the coronal plane of 1298-005-LC reveals DORV {S,D,D} with subaortic VSD, AVSD, and interrupted aortic arch (type B).
Click thumbnail to play movie.		b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Mutant 1298-003-6 (E16.5) exhibits malalignment of the great arteries indicating double outlet right ventricle (DORV).b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
EFIC Summaryb2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Serial 2D EFIC image stack in the coronal plane of 1298-003-6 (E16.5) reveals DORV {S,D,D}, subaortic VSD
Click thumbnail to play movie.		b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
2D micro-CT image stack in the coronal plane of 1289-003-6 (E16.5) reveals DORV and subaortic VSD
Click thumbnail to play movie.		b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Mutant 1298-003-6 (E16.5) exhibits hydronephrosis and hydroureter of the right kidney.b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Mutant 1298-003-6 exhibits hydronephrosis with hydroureter in the right kidney.b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Mutant 1298-002-LA exhibits malaligned parallel positioning of the great arteriesb2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
EFIC Summaryb2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Serial 2D EFIC image stack in the coronal plane of 1298-002-LA reveals DORV {S,D,D} with subaortic VSD.
Click thumbnail to play movie.		b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
2D serial micro-CT image stack in the coronal plane of 1298-002-LA reveals DORV {S,D,D} and subaortic VSD
Click thumbnail to play movie.		b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Mutant 1298-002-LC exhibits enlarged, possibly cystic left kidney.b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Mutant 1298-002-LA exhibits hydronephrosis with small glomerular cysts.b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Kidney from mutant 1298-002-LA exhibits hydronephrosis with glomerular cysts.b2b1298Clo/b2b1298CloC57BL/6J-b2b1298Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory