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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b1117Clo
Name: Mutant line 1117; Bench to Bassinet Program (B2B/CVDC), mutation 1117 Cecilia Lo
MGI ID: MGI:5437730
Synonyms: Argh
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1117-007-NA shows a single great artery arising from ventricles with right sided aortic archb2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.1Clo/b2b1117.1CloC57BL/6J-b2b1117.1Clo
Mutant 1117-005-NA shows enlarged great artery with abnormal aortic arch and congested atriab2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.1Clo/b2b1117.1CloC57BL/6J-b2b1117.1Clo
Mutant 1117-007-NA shows mid-facial cleftb2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.1Clo/b2b1117.1CloC57BL/6J-b2b1117.1Clo
Mutant 1117-007-NA exhibits micrognathia with recessed lower jawb2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.1Clo/b2b1117.1CloC57BL/6J-b2b1117.1Clo
EFIC Summaryb2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.1Clo/b2b1117.1CloC57BL/6J-b2b1117.1Clo
Serial 2D EFIC image stack in the coronal plane of 1117-007-NA reveals pulmonary atresia, VSD, MAPCA, and right aortic arch
Click thumbnail to play movie.		b2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.1Clo/b2b1117.1CloC57BL/6J-b2b1117.1Clo
EFIC Summaryb2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.1Clo/b2b1117.1CloC57BL/6J-b2b1117.1Clo
Serial 2D EFIC image stack of mutant 1117-005-NA in coronal plane reveals pulmonary atresia, VSD, and MAPCA, dysplastic aortic valve and short acsending aorta
Click thumbnail to play movie.		b2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.1Clo/b2b1117.1CloC57BL/6J-b2b1117.1Clo
Serial 2D EFIC image stack in the transverse plane of 1117-005-NA reveals MAPCA with aortic arch to right lung
Click thumbnail to play movie.		b2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.1Clo/b2b1117.1CloC57BL/6J-b2b1117.1Clo
Mutant 1117-006-ND exhibits evidence of cardiac hypertrophy, confirmed by EFIC histopathologyb2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.2Clo/b2b1117.2CloC57BL/6J-b2b1117.2Clo
EFIC Summaryb2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.2Clo/b2b1117.2CloC57BL/6J-b2b1117.2Clo
Serial 2D EFIC image stack in the coronal plane of mutant 1117-006-ND exhibits biventricular hypertrophy
Click thumbnail to play movie.		b2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.2Clo/b2b1117.2CloC57BL/6J-b2b1117.2Clo
MicroCT serial image stack in the coronal view of mutant 1117-006-ND shows biventricular hypertrophy
Click thumbnail to play movie.		b2b1117Clo/b2b1117CloC57BL/6J-b2b1117Clo
b2b1117.2Clo/b2b1117.2CloC57BL/6J-b2b1117.2Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/29/2024
MGI 6.24 		The Jackson Laboratory