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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b1625Clo
Name: Mutant line 1625; Bench to Bassinet Program (B2B/CVDC), mutation 1625 Cecilia Lo
MGI ID: MGI:5438060
Synonyms: Tupac
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1625-002-NB displays malpositioning of the great arteries which was confirmed to be overriding aorta by EFIC imagingb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
EFIC Summaryb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
Serial 2D EFIC image stack in the coronal plane of 1625-002-NB reveals overriding aorta, unbalanced AVSD, and hypoplastic RV
Click thumbnail to play movie.		b2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
Serial 2D micro-MRI image stack in the coronal plane of 1625-002-NB reveals AVSD and hypoplastic RV
Click thumbnail to play movie.		b2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
Mutant 1625-002-NB displays malrotation of the atria and hypoplastic right ventricleb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
Mutant 1625-002-NB displays a duplex left kidneyb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
Mutant 1625-006-1 (E 15.5) displays parallel positioning of the great arteries, which was shown to be DORV by EFIC imagingb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
Mutant 1625-006-1 (E 15.5) displays parallel positioning of the great arteriesb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
EFIC Summaryb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
Serial 2D EFIC image stack in the coronal plane of 1625-006-1 (E15.5) reveals DORV with suboartic VSD and biventricular hypertrophy
Click thumbnail to play movie.		b2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
Mutant 1625-002-NA showed malalignment of the great arteries, which was shown by EFIC imaging to be DORVb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
EFIC Summaryb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
Serial 2D EFIC image stack in the coronal plane of 1625-002-NA reveals DORV {S,D,D} and AVSD
Click thumbnail to play movie.		b2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
Serial 2D EFIC image stack of 1625-002-NA in the transverse plane reveals DORV {S,D,D} and AVSD
Click thumbnail to play movie.		b2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Snx17b2b1625.1Clo/Snx17b2b1625.1CloC57BL/6J-Snx17b2b1625.1Clo
EFIC Summaryb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Lrp2b2b1625.2Clo/Lrp2b2b1625.2CloC57BL/6J-Lrp2b2b1625.2Clo
Serial 2D EFIC image stack of 1625-007-1 (E15.5) in the coronal plane reveals PTA (type 1), right aortic arch, isolated left subclavian artery forming incomplete vascular ring
Click thumbnail to play movie.		b2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Lrp2b2b1625.2Clo/Lrp2b2b1625.2CloC57BL/6J-Lrp2b2b1625.2Clo
Mutant 1625-007-1 (E15.5) has hydrops and anopthalmiab2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Lrp2b2b1625.2Clo/Lrp2b2b1625.2CloC57BL/6J-Lrp2b2b1625.2Clo
Mutant 1625-007-1 (E15.5) presents with hydrops and microganthia, low-set ears and omphaloceleb2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Lrp2b2b1625.2Clo/Lrp2b2b1625.2CloC57BL/6J-Lrp2b2b1625.2Clo
Mutant 1625-007-1 (E15.5) has microganthia and anopthalmiab2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Lrp2b2b1625.2Clo/Lrp2b2b1625.2CloC57BL/6J-Lrp2b2b1625.2Clo
Mutant 1625-007-1 (E15.5) has low-set ears, microstomia, and anopthalmiab2b1625Clo/b2b1625CloC57BL/6J-b2b1625Clo
Lrp2b2b1625.2Clo/Lrp2b2b1625.2CloC57BL/6J-Lrp2b2b1625.2Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory