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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b1709Clo
Name: Mutant line 1709; Bench to Bassinet Program (B2B/CVDC), mutation 1709 Cecilia Lo
MGI ID: MGI:5438064
Synonyms: Durante
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Necropsy of 1709-003-MLA shows hypoplastic LV.b2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Serial 2D micro-MRI image stack in the coronal plane of 1709-003-MLA reveals hypoplastic left ventricle, perimembranous and muscular VSDs
Click thumbnail to play movie.		b2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
EFIC Summaryb2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Serial 2D EFIC image stack in the coronal plane of 1709-003-MLA reveals overriding aorta, hypoplastic mitral valve (stenosis), hypoplastic LV, perimembranous and muscular VSDs, HLHS variant.
Click thumbnail to play movie.		b2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Serial 2D EFIC image stack in the transverse plane of 1709-003-MLA reveals hypoplastic mitral valve (stenosis), hypoplastic LV, perimembranous and muscular VSDs.
Click thumbnail to play movie.		b2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Serial 2D EFIC image stack in the sagittal plane of 1709-003-MLA shows hypoplastic LV, overriding aorta, subaortic VSD.
Click thumbnail to play movie.		b2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Serial 2D micro-MRI image stack in the coronal plane of 1709-002-NB reveals coronary artery fistula
Click thumbnail to play movie.		b2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
EFIC Summaryb2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Serial 2D EFIC image stack in the coronal plane of 1709-002-NB reveals coronary artery fistula (RCA to LV)
Click thumbnail to play movie.		b2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
EFIC Summaryb2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Serial 2D-EFIC image stack of 1709-002-NC in the coronal plane reveals overriding aorta, perimembranous and muscular VSDs
Click thumbnail to play movie.		b2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
EFIC Summaryb2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Serial 2D-EFIC image stack of 1709-004-NA in the coronal plane reveals vascular ring with hypoplastic transverse aorta and ductus arteriosus, biventricular hypertrophy
Click thumbnail to play movie.		b2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Mutant 1709-004-NA exhibit a prominent proboscis with low set ears, no mouth and a single eye-like structure along the midlineb2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Mutant 1709-004-NA exhibit a prominent proboscis with low set ears, no mouth and a single eye-like structure along the midlineb2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Mutant 1709-004-NA exhibit a prominent proboscis with low set ears, no mouth and a single eye-like structure along the midlineb2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Mutant 1709-004-NA exhibit left aortic arch with hypoplastic transverse aorta forming vascular ring with ductus arteriosusb2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Mutant 1709-004-NA exhibit blood congested atria, and superior and inferior vena cavab2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Serial 2D micro-MRI image stack of 1709-004-NA in the coronal plane reveals craniofacial dysplasia, holoprosencephaly, interrupted aortic arch (Type B)
Click thumbnail to play movie.		b2b1709Clo/b2b1709CloC57BL/6J-b2b1709Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory