Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Kit^tm4.1Bsm
Name:	KIT proto-oncogene receptor tyrosine kinase; targeted mutation 4.1, Peter Besmer
MGI ID:	MGI:5442620
Synonyms:	Kit^{V558delta;T669I}

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Reduced length of cecum in Kit^tm4.1Bsm/Kit⁺ mice and cecal tumors in Kit^tm4.1Bsm/Kit⁺ and Kit^tm5.1Bsm/Kit⁺	Kit^tm4.1Bsm/Kit⁺	involves: 129S1/Sv * C57BL/6J * FVB/N
		Kit^tm5.1Bsm/Kit⁺	involves: 129S1/Sv * C57BL/6J * FVB/N
	Cecal gastrointestinal stromal tumor and gastric/colonic interstatial cell of Cajal hyperplasia in Kit^tm5.1Bsm/Kit⁺ and Kit^tm4.1Bsm/Kit⁺ mice	Kit^tm4.1Bsm/Kit⁺	involves: 129S1/Sv * C57BL/6J * FVB/N
		Kit^tm5.1Bsm/Kit⁺	involves: 129S1/Sv * C57BL/6J * FVB/N
	Alopecia and 'red paw' in Kit^tm4.1Bsm/Kit⁺ mice	Kit^tm4.1Bsm/Kit⁺	involves: 129S1/Sv * C57BL/6J * FVB/N
	Increase in mast cells and erythrocytic congestion of liver blood vessels in Kit^tm4.1Bsm/Kit⁺ mice	Kit^tm4.1Bsm/Kit⁺	involves: 129S1/Sv * C57BL/6J * FVB/N

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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