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Phenotype Images associated with this Allele
Nomenclature
Symbol: Rspo3tm1.2Jcob
Name: R-spondin 3; targeted mutation 1.2, John Cobb
MGI ID: MGI:5443965
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Developmental arrest and vascular defects in Rspo3tm1.2Jcob/Rspo3tm1.2Jcob embryosRspo3tm1.2Jcob/Rspo3tm1.2Jcobinvolves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL
Rspo2ftls/Rspo2ftls Rspo3tm1.1Jcob/Rspo3tm1.2Jcob Tg(Prrx1-cre)1Cjt/0 double mutants have more severe limb defects than single mutantsRspo3tm1.1Jcob/Rspo3tm1.2Jcob
Tg(Prrx1-cre)1Cjt/0		involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL
Rspo2ftls/Rspo2ftls
Rspo3tm1.1Jcob/Rspo3tm1.2Jcob
Tg(Prrx1-cre)1Cjt/0		involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL
Rspo2ftls/Rspo2ftlsNot Specified
Limb abnormalities in Rspo2ftls/Rspo2ftls and Rspo2ftls/Rspo2ftls Rspo3tm1.1Jcob/Rspo3tm1.2Jcob Tg(Prrx1-cre)1Cjt/0 newbornsRspo2ftls/Rspo2ftls
Rspo3tm1.1Jcob/Rspo3tm1.2Jcob
Tg(Prrx1-cre)1Cjt/0		involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL
Rspo2ftls/Rspo2ftlsNot Specified
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory