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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b1430Clo
Name: Mutant line 1430; Bench to Bassinet Program (B2B/CVDC), mutation 1430 Cecilia Lo
MGI ID: MGI:5446156
Synonyms: Donner
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1430-014-NC has a right aortic arch and hypoplastic aorta.b2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
EFIC Summaryb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Serial 2D EFIC image stack in the coronal plane of 1430-014-NC reveals HLHS, hypoplastic aorta, hypolastic LV, pmVSD, and right aortic arch.
Click thumbnail to play movie.		b2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-004-NA shows globular ventricles and anterior aorta, which is diagnosed as TGA by EFIC imagingb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-014-NC presents with a short snoutb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-014-NC shows slight hydronephrosisb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
EFIC Summaryb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Serial 2D EFIC image stack of 1430-004-NA in the coronal plane reveals d-TGA and biventricular hypertrophy
Click thumbnail to play movie.		b2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Serial 2D CT coronal image stack of 1430-004-NA reveals d-TGA (type-I)
Click thumbnail to play movie.		b2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-004-NA presents with a short snoutb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-004-NA is missing the right kidneyb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Left kidney of mutant 1430-004-NA has small to moderate sized cysts in the tubulesb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-015-NA presents with parallel outflow tracts which is diagnosed as DORV by EFIC imagingb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
EFIC Summaryb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Serial 2D EFIC image stack in the coronal plane of 1430-015-NA reveals double aortic arch, DORV, and malalignment of OFT (side by side)
Click thumbnail to play movie.		b2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-015-NA shows cleft palateb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-015-NA has an abnormal sternum that appears compressed and is malalignedb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-015-NA presents with cystic kidneys which is confirmed by histologyb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Kidneys of mutant 1430-015-NA presents with moderate number of cysts or dilations in the tubules (right kidney shown)b2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-015-ND presents with parallel outflow tracts and thickened ventricular walls, which is diagnosed as DORV and biventricular hypertrophy by EFIC imagingb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
EFIC Summaryb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Serial 2D EFIC image stack of 1430-015-ND in the coronal plane reveals DORV, subaortic VSD and biventricular hypertrophy
Click thumbnail to play movie.		b2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-015-ND shows cleft palateb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Mutant 1430-015-ND exhibits kidney agenesisb2b1430Clo/b2b1430CloC57BL/6J-b2b1430Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory