Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Prdm1^b2b1765Clo
Name:	PR domain containing 1, with ZNF domain; Bench to Bassinet Program (B2B/CVDC), mutation 1765 Cecilia Lo
MGI ID:	MGI:5446157
Synonyms:	Jigsaw

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 1765-005-6 (E15.5) exhibits a hypoplastic LV and hypoplastic aortic arch.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Mutant 1765-005-6 (E15.5) has a small hypertrophic LV	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	EFIC Summary	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Serial 2D EFIC image stack of 1765-005-6 (E15.5) in the coronal view shows suspected aortic valve atresia, hypertrophic obstructive cardiomyopathy, and small mitral annulus Click thumbnail to play movie.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Mutant 1765-007-NA exhibits right aortic arch	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	EFIC summary	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Serial 2D EFIC image stack of 1765-007-NA in the coronal plane reveals AVSD, right aortic arch, aberrant left subclavian artery from main PA Click thumbnail to play movie.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Mutant 1765-005-1 (E15.5) shows malalignment of the great arteries with hypoplastic transverse arch and dilated pulmonary outflow.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	EFIC summary	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Serial 2D EFIC image stack in the coronal plane of mutant 1765-005-1 (E15.5) reveals overriding aorta, AVSD, hypoplastic transverse aortic arch, and biventricular hypertrophy Click thumbnail to play movie.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Mutant 1765-006-2 (E14.5) exhibits malalignment of the great arteries with abnormal right sided aortic arch (RAA) indicating possible vascular ring.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	EFIC summary	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Serial 2D EFIC image stack in the coronal plane of mutant 1765-006-2 (E14.5) reveals double outlet right ventricle (DORV), right aortic arch (RAA), and vascular ring Click thumbnail to play movie.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo

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