Phenotype Images associated with this Allele - MGI

About Help FAQ

Phenotype Images associated with this Allele

Nomenclature

Symbol:	Prdm1^b2b1765Clo
Name:	PR domain containing 1, with ZNF domain; Bench to Bassinet Program (B2B/CVDC), mutation 1765 Cecilia Lo
MGI ID:	MGI:5446157
Synonyms:	Jigsaw

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 1765-005-6 (E15.5) exhibits a hypoplastic LV and hypoplastic aortic arch.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Mutant 1765-005-6 (E15.5) has a small hypertrophic LV	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	EFIC Summary	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Serial 2D EFIC image stack of 1765-005-6 (E15.5) in the coronal view shows suspected aortic valve atresia, hypertrophic obstructive cardiomyopathy, and small mitral annulus Click thumbnail to play movie.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Mutant 1765-007-NA exhibits right aortic arch	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	EFIC summary	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Serial 2D EFIC image stack of 1765-007-NA in the coronal plane reveals AVSD, right aortic arch, aberrant left subclavian artery from main PA Click thumbnail to play movie.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Mutant 1765-005-1 (E15.5) shows malalignment of the great arteries with hypoplastic transverse arch and dilated pulmonary outflow.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	EFIC summary	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Serial 2D EFIC image stack in the coronal plane of mutant 1765-005-1 (E15.5) reveals overriding aorta, AVSD, hypoplastic transverse aortic arch, and biventricular hypertrophy Click thumbnail to play movie.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Mutant 1765-006-2 (E14.5) exhibits malalignment of the great arteries with abnormal right sided aortic arch (RAA) indicating possible vascular ring.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	EFIC summary	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo
	Serial 2D EFIC image stack in the coronal plane of mutant 1765-006-2 (E14.5) reveals double outlet right ventricle (DORV), right aortic arch (RAA), and vascular ring Click thumbnail to play movie.	Prdm1^b2b1765Clo/Prdm1^b2b1765Clo	C57BL/6J-Prdm1^b2b1765Clo

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24