Phenotype Images associated with this Allele

Nomenclature

Symbol:	Dnah11^b2b1775Clo
Name:	dynein, axonemal, heavy chain 11; Bench to Bassinet Program (B2B/CVDC) mutation 1775, Cecilia Lo
MGI ID:	MGI:5446158
Synonyms:	Blindfold, Dnahc11^c.6489+2T

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 1775-005-LA displays dextrocardia, inverted lung lobe, malrotation of intestines	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	EFIC Summary	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Serial 2D EFIC image stack of 1775-005-LA in the coronal view reveals dextrocardia {A,L,L}, dual IVC, inverted hemiazygous venous connection Click thumbnail to play movie.	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-005-LA displays malaligned sternal vertebrate	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-005-LA displays inverted anterior-posterior positioning of the kidneys, with left kidney higher than right. Also note abnormal dilated vessel near right adrenal gland.	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1774-005-LA displays intestinal malrotation, abnormal color (pale) left liver lobe	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-005-LA shows dyskinetic airway cilia motility as well as hyperkinetic airway cilia motility Click thumbnail to play movie.	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-005-LA shows dyskinetic and hyperkinetic airway cilia Click thumbnail to play movie.	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-003-NA with dextrocardia and ambiguous lung lobation with possible diaphragmatic herniation of the liver on the right.	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Serial 2D micro-CT image stack of 1775-003-NA in the coronal plane reveals heterotaxy, dextrocardia {A,L,L} inverted hemiazygous venous connection, hepatic vein connects to left side atrium. Abnormal lung lobation indicative of left pulmonary isomerism (2 right lobes, and single left lobe), abnormal liver position, left sided stomach. Click thumbnail to play movie.	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-003-NA exhibits hypoplastic spleen	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-002-LA displays situs inversus totalis	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-002-LA exhibits dyskinetic airway cilia with patches of immotile cilia Click thumbnail to play movie.	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-018-6 (E14.5) is a situs mutant with dextrocardia and dextrogastria	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-018-6 (E14.5) exhibits dextrocardia and DORV which is diagnosed by EFIC	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	EFIC summary	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Serial 2D EFIC image stack in the coronal plane of 1775-018-6 (E14.5) shows dextrocardia, DORV, and subaortic VSD Click thumbnail to play movie.	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-018-9 (E14.5) is a situs mutant with dextrocardia and dextrogastria	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Mutant 1775-018-9 (E14.5) has dextrocardia and DORV diagnosed by EFIC	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	EFIC summary	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo
	Serial 2D EFIC image stack in the coronal plane of 1775-018-9 (E14.5) shows dextrocardia, DOmRV, and subaortic VSD Click thumbnail to play movie.	Dnah11^b2b1775Clo/Dnah11^b2b1775Clo	C57BL/6J-Dnah11^b2b1775Clo

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