Phenotype Images associated with this Allele
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Nomenclature
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Symbol:
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b2b1963Clo
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Name:
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Mutant line 1963;
Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
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MGI ID:
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MGI:5467354
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Synonyms:
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Fez
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Images for
Allele
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Click images for details
 | Mutant 1963-002-3 (E16.5) exhibits a hypoplastic transverse arch and hypoplastic LV. | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | EFIC summary | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | Serial 2D EFIC image stack in the coronal plane of 1963-002-3 (E16.5) reveals HLHS, hypoplastic left ventricle, small mitral valve, left ventricular outflow tract obstruction, hypoplastic transverse aortic arch. Note the stack that showed aorta arising from RV is an artifact. Please refer to ultrasound imaging (http://www.informatics.jax.org/image/MGI:5644802), which clearly indicated aorta arising from left ventricle.
Click thumbnail to play movie. | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | Color flow spectral Doppler imaging of mutant 1963-002 in the sagittal view shows Ao emerging from hypoplastic LV, also note left outflow tract obstruction.
Click thumbnail to play movie. | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | Color flow spectral Doppler imaging of mutant 1963-002 in the sagittal view shows Ao emerging from hypoplastic LV | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | Color flow spectral Doppler imaging of mutant 1963-002 in the coronal view shows small size of mitral valve, small LV, no flow was detected in transverse arch, indicating hypoplastic LV, possible hypoplastic arch. | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | Mutant 1963-002-3 (E16.5) has hypoplastic thymus | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | Mutant 1963-002-3 (E16.5) has microphthalmia, clefting of the mouth and cleft palate | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | Mutant 1963-002-1 (E16.5) shows a hypoplastic transverse arch and LV hypertrophy | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | EFIC summary | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | Serial 2D EFIC image stack on the coronal plane of 1963-002-1 (E16.5) reveals DORV, hypoplastic transverse aortic arch, LV hypertrophy, and pmVSD
Click thumbnail to play movie. | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
 | Mutant 1963-002-1 (E16.5) exhibits exencephaly with anophthalmia, and micrognathia with recessed lower jaw. | b2b1963Clo/b2b1963Clo | C57BL/6J-b2b1963Clo |
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