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Phenotype Images associated with this Allele
Nomenclature
Symbol: Nmnat2Tn(sb-Tyr)2172.P9KK4BOve
Name: nicotinamide nucleotide adenylyltransferase 2; targeted mutation 2172.P9KK4B, Paul A Overbeek
MGI ID: MGI:5473270
Synonyms: Nmnat2blad, OVB2172-P9KK4B
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Hunched posture with enlarged abdomen in Nmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOve E18.5 pupsNmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOveinvolves: FVB/N
Distended bladder, urogenital tract damage, underdeveloped diaphragm, and decreased skeletal muscle mass in Nmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOve E18.5 pupsNmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOveinvolves: FVB/N
Loss of facial motoneurons in Nmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOve E18.5 pupsNmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOveinvolves: FVB/N
Dorsal root ganglion is reduced in size in E18.5 Nmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOve pupsNmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOveinvolves: FVB/N
Increase in pyknotic neurons and decrease in lumbar motoneuron numbers in E13.5 Nmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOve embryosNmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOveinvolves: FVB/N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory