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Phenotype Images associated with this Allele
Nomenclature
Symbol: Mob1atm1.1Asuz
Name: MOB kinase activator 1A; targeted mutation 1.1, Akira Suzuki
MGI ID: MGI:5473804
Synonyms: Mob1aflox
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Skin and hair abnormalities and large paws in tamoxifen treated Mob1atm1.1Asuz/Mob1atm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi miceMob1atm1.1Asuz/Mob1atm1.1Asuz
Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi
Tg(KRT14-cre/ERT)20Efu/0		involves: 129P2/OlaHsd * C57BL/6 * CD-1
Increased proliferation, repressed apoptosis, and impaired contact inhibition and chromosome segregation in Mob1atm1.1Asuz/Mob1atm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi keratinocytesMob1atm1.1Asuz/Mob1atm1.1Asuz
Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi
Tg(KRT14-cre/ERT)20Efu/0		involves: 129P2/OlaHsd * C57BL/6 * CD-1
Hair follicle and interfollicular epidermis hyperplasia in tamoxifen treated Mob1atm1.1Asuz/Mob1atm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi miceMob1atm1.1Asuz/Mob1atm1.1Asuz
Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi
Tg(KRT14-cre/ERT)20Efu/0		involves: 129P2/OlaHsd * C57BL/6 * CD-1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory