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Phenotype Images associated with this Allele
Nomenclature
Symbol: Mfsd2atm1Dls
Name: MFSD2 lysolipid transporter A, lysophospholipid; targeted mutation 1, David L Silver
MGI ID: MGI:5474960
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Shortened and disorganized outer rod segments and swollen retinal pigment epithelium in Mfsd2atm1Dls/Mfsd2atm1Dls miceMfsd2atm1Dls/Mfsd2atm1DlsB6.Cg-Mfsd2atm1Dls
Disorganization of the outer rod segment, swollen retinal pigment epithelium and disorganization of retinal pigment epithelium villi in Mfsd2atm1Dls/Mfsd2atm1Dls miceMfsd2atm1Dls/Mfsd2atm1DlsB6.Cg-Mfsd2atm1Dls
Activated microglia in Mfsd2atm1Dls/Mfsd2atm1Dls miceMfsd2atm1Dls/Mfsd2atm1DlsB6.Cg-Mfsd2atm1Dls
Rhodopsin is mislocalized to the outer nuclear layer in Mfsd2atm1Dls/Mfsd2atm1Dls retinaMfsd2atm1Dls/Mfsd2atm1DlsB6.Cg-Mfsd2atm1Dls
Increased brown adipose tissue beta-oxidation in Mfsd2atm1Dls/Mfsd2atm1Dls miceMfsd2atm1Dls/Mfsd2atm1DlsB6.Cg-Mfsd2atm1Dls
Decreased liver triglycerides in Mfsd2atm1Dls/Mfsd2atm1Dls miceMfsd2atm1Dls/Mfsd2atm1DlsB6.Cg-Mfsd2atm1Dls
Decreased adiposity in Mfsd2atm1Dls/Mfsd2atm1Dls miceMfsd2atm1Dls/Mfsd2atm1DlsB6.Cg-Mfsd2atm1Dls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory