Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Plxnd1^b2b1863Clo
Name:	plexin D1; Bench to Bassinet Program (B2B/CVDC), mutation 1863 Cecilia Lo
MGI ID:	MGI:5476170
Synonyms:	Snowman

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 1863-002-4 (E16.5) has a hypoplastic transverse arch and malaligned great arteries	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Mutant 1863-002-4 (E16.5) shows hypoplastic arch with malaligned great arteries	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Mutant 1863-002-4 (E16.5) has hypoplastic thymus	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	EFIC Summary	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Serial 2D EFIC image stack in the coronal plane of mutant 1863-002-4 (E16.5) reveals DORV, subaortic VSD, and hypoplastic transverse aortic arch Click thumbnail to play movie.	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Mutant 1863-004-1 (E17.5) shows PTA and a right aortic arch	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Mutant 1863-004-1 (E17.5) has a misshapened and mislocalized thymus	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Mutant 1863-004-1 (E17.5) shows a left duplex kidney	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	EFIC Summary	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Serial 2D EFIC image stack of 1863-004-1 (E17.5) in the coronal plane reveals Truncus Arterosus (Van Praagh A2) {A,D,D}, AVSD, right Aortic Arch, double IVS, myocardial non-compaction Click thumbnail to play movie.	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Mutant 1863-004-2 (E17.5) exhibits PTA with a right aortic arch	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Mutant 1863-004-2 (E17.5) has a hypoplastic and misshapened thymus	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Mutant 1863-004-2 (E17.5) shows left kidney agenesis	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Mutant 1863-004-2(E17.5) exhibits a cleft palate which is consistent with DiGeorge syndrome	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	EFIC Summary	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo
	Serial 2D EFIC image stack of 1863-004-2 (E17.5) in the coronal plane reveals Persistent Truncus Arterosus (Van Praagh A2), AVSD {A,D,D}, right aortic arch, dual IVC, myocardial non-compaction Click thumbnail to play movie.	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo

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