| Mutant 1863-002-4 (E16.5) has a hypoplastic transverse arch and malaligned great arteries | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Mutant 1863-002-4 (E16.5) shows hypoplastic arch with malaligned great arteries | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Mutant 1863-002-4 (E16.5) has hypoplastic thymus | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| EFIC Summary | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Serial 2D EFIC image stack in the coronal plane of mutant 1863-002-4 (E16.5) reveals DORV, subaortic VSD, and hypoplastic transverse aortic arch Click thumbnail to play movie. | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Mutant 1863-004-1 (E17.5) shows PTA and a right aortic arch | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Mutant 1863-004-1 (E17.5) has a misshapened and mislocalized thymus | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Mutant 1863-004-1 (E17.5) shows a left duplex kidney | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| EFIC Summary | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Serial 2D EFIC image stack of 1863-004-1 (E17.5) in the coronal plane reveals Truncus Arterosus (Van Praagh A2) {A,D,D}, AVSD, right Aortic Arch, double IVS, myocardial non-compaction Click thumbnail to play movie. | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Mutant 1863-004-2 (E17.5) exhibits PTA with a right aortic arch | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Mutant 1863-004-2 (E17.5) has a hypoplastic and misshapened thymus | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Mutant 1863-004-2 (E17.5) shows left kidney agenesis | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Mutant 1863-004-2(E17.5) exhibits a cleft palate which is consistent with DiGeorge syndrome | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| EFIC Summary | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |
| Serial 2D EFIC image stack of 1863-004-2 (E17.5) in the coronal plane reveals Persistent Truncus Arterosus (Van Praagh A2), AVSD {A,D,D}, right aortic arch, dual IVC, myocardial non-compaction Click thumbnail to play movie. | Plxnd1b2b1863Clo/Plxnd1b2b1863Clo | C57BL/6J-Plxnd1b2b1863Clo |