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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b1876Clo
Name: Mutant line 1876; Bench to Bassinet Program (B2B/CVDC), mutation 1876 Cecilia Lo
MGI ID: MGI:5476172
Synonyms: Boombox
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1876-002-1 (E14.5) exhibits parallel outflow tracts which is confirmed by EFIC imaging to be DORVb2b1876Clo/b2b1876CloC57BL/6J-b2b1876Clo
EFIC Summaryb2b1876Clo/b2b1876CloC57BL/6J-b2b1876Clo
Serial 2D EFIC image stack of 1876-002-1 (E14.5) in the coronal plane reveals DORV, subaortic AVSD, and spongy ventricles
Click thumbnail to play movie.		b2b1876Clo/b2b1876CloC57BL/6J-b2b1876Clo
Color flow spectral Doppler imaging of mutant 1876-002-1 (E14.5) in the frontal view shows PA and majority of aorta arising from RV with VSD, suggesting DORV with subaortic VSDb2b1876Clo/b2b1876CloC57BL/6J-b2b1876Clo
2D imaging of mutant 1876-002-1 (E14.5) in the transverse view shows atrioventricular septal defectb2b1876Clo/b2b1876CloC57BL/6J-b2b1876Clo
Color flow imaging of mutant 1876-002-1 (E14.5) in the transverse view shows atrioventricular septal defect and common atrioventricular valve (AV) regurgitation which suggests atrioventricular septal defect (AVSD)b2b1876Clo/b2b1876CloC57BL/6J-b2b1876Clo
Mutant 1876-002-3 (E14.5) shows an enlarged right atrium and malpositioned outflow tractb2b1876Clo/b2b1876CloC57BL/6J-b2b1876Clo
EFIC Summaryb2b1876Clo/b2b1876CloC57BL/6J-b2b1876Clo
Serial 2D EFIC image stack in the coronal plane of mutant 1876-002-3 (E14.5) reveals atrioventricular septal defect (AVSD), muscular VSD (mVSD), and spongy ventricles
Click thumbnail to play movie.		b2b1876Clo/b2b1876CloC57BL/6J-b2b1876Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/24/2024
MGI 6.24 		The Jackson Laboratory