About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b1879Clo
Name: Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
MGI ID: MGI:5476173
Synonyms: Carter
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1879-002-NA shows abnormal placement of the outflow with malformed pulmonary trunk and is diagnosed with DORV by EFIC imagingb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
EFIC Summaryb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Serial 2D EFIC image stack in the coronal plane of 1879-002-NA reveals DORV, subaortic VSD, and biventricular hypertrophy
Click thumbnail to play movie.		b2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-002-NA has a short snout, micrognathia, domed-shaped head, short limbs, and abnormally attached hindlimbsb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-002-NA has midline defect with unfused sternumb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-002-1 (E16.5) exhibits abnormally attached hindlimbsb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-002-1 (E16.5) exhibits a cleft palateb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-002-1 (E16.5) presents with an unfused sternumb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
EFIC Summaryb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Serial 2D EFIC image stack in the coronal plane of mutant 1879-002-1 (E16.5) reveals overriding aorta, PA hypoplasia, and biventricular hypertrophy
Click thumbnail to play movie.		b2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Color flow spectral Doppler imaging of mutant 1879-002-1 (E16.5) in the saggital view shows aorta overriding on the ventricular septum, VSD, blood flow only can be detected in aorta. Notice a small vessel beside aorta, but no blood flow inside. This together suggests PA, VSD
Click thumbnail to play movie.		b2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Snapshot of video of Color flow spectral Doppler imaging for mutant 1879-002-1 (E16.5) in the sagittal view shows aorta overriding on the ventricular septum, VSD, blood flow only can be detected in aorta. Notice a small vessel beside aorta, but no blood flow inside. This together suggests PA, VSDb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-004-2 (E17.5) presents with hydrops, short snout, and abnormal flexure of the hindlimbsb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-004-2 (E17.5) exhibits a cleft palateb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-004-2 (E17.5) has hypoplastic thymusb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-004-2 (E17.5) has malaligned outflow tracts shown to be DORV by EFIC imagingb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
EFIC Summaryb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Serial 2D EFIC image stack of 1879-004-2 (E17.5) in the coronal plane reveals DORV {S,D,D}, subaortic AVSD, ventricular myocardial non-compaction
Click thumbnail to play movie.		b2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-004-1 (E17.5) presents with hydrops and abnormally attached hindlimbsb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-004-1 (E17.5) exhibits a hypoplastic thymusb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-004-1 (E17.5) exhibits a hypoplastic transverse arch and overriding aorta, which was confirmed by EFIC imagingb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
EFIC Summaryb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Serial 2D EFIC image stack in the coronal plane of mutant 1879-004-1 (E17.5) reveals overriding aorta, pmVSD, hypoplastic Ao, and ventricular myocardial non-compaction
Click thumbnail to play movie.		b2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
Adamts6b2b1879.1Clo/Adamts6b2b1879.1CloC57BL/6J-Adamts6b2b1879.1Clo
Mutant 1879-006-NB shows kidney agenesisb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
b2b1879.2Clo/b2b1879.2CloC57BL/6J-b2b1879.2Clo
Mutant 1879-006-NC shows kidney agenesisb2b1879Clo/b2b1879CloC57BL/6J-b2b1879Clo
b2b1879.2Clo/b2b1879.2CloC57BL/6J-b2b1879.2Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory